E. coli: Genomics, Evolution and Pathogenesis
Language: English
Published by Academic Press, 2002
- Hardcover
- New
Seller: Basi6 International, Irving, TX, U.S.A.Basi6 International
AbeBooks seller since June 24, 2016
Condition: New
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- Title
- E. coli: Genomics, Evolution and Pathogenesis
- Author
- 0
- Publisher
- Academic Press
- Publication year
- 2002
- Condition
- Brand New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0122207513
- ISBN 13
- 9780122207518
Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods ― such as undercooked meat and unpasteurized fruit juice ― and has attracts much attention when serious outbreaks occur.
E. coli is capable of causing a wide variety of diseases ― from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness.
Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research.
- Single source of information of E. coli pathogenesis
- Expert authors
- Comprehensive coverage
- Molecular mechanisms
- Biology, evolution and genomics
- Recent advances
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About the Author
Dr. Donnenberg’s research has focused on the molecular pathogenesis of infections due to Escherichia coli and on the biogenesis and function of bacterial surface appendages called Type IV Pili that are used by many pathogens to adhere to host cell surfaces. His work has been continuously funded by the National Institutes of Health for over twenty years and has resulted in the publication of over one hundred original manuscripts, reviews, and book chapters. He is a Fellow of the Infectious Diseases Society of America and the American Academy of Microbiology and a member of the American Society for Clinical Investigation. He is a recipient of the Oswald Avery Award from the Infectious Diseases Society of America.
Dr. Donnenberg is an active Infectious Diseases clinician and directs the Medical Scientist (MD/PhD) Program at the University of Maryland. He is also active in medical education and was an inaugural member of the Pass and Susel Academy of Academic Excellence at the University of Maryland.
"About the title" may belong to another edition of this title.
Basi6 International
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AbeBooks seller since June 24, 2016
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