Dynamic protein assemblies in homologous recombination : studied by single-molecule techniques

Language: English

Published by VDM Verlag Dr. Müller, 2009

3639189655 / 9783639189650

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - What happens when your DNA breaks This thesis describes experimental work on the single-molecule level focusing on the interaction between DNA and DNA-repair proteins, in particular bacterial RecA and human Rad51, involved in homologous recombination. Homologous recombination and its central event of DNA strand exchange are essential processes in all living organisms for generating genetic diversity and for repairing potentially disastrous DNA breaks. Several cancer-prone genetic diseases are associated with homologous recombination dysfunction or deficiency. With the use of single-molecule techniques like magnetic tweezers and atomic force microscopy, the complex mechanism of the DNA repair pathway of homologous recombination is slowly unraveled.

Seller Inventory # 9783639189650

Title
Dynamic protein assemblies in homologous recombination : studied by single-molecule techniques
Author
Thijn van der Heijden
Publisher
VDM Verlag Dr. Müller
Publication year
2009
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3639189655
ISBN 13
9783639189650
Item weight
325 grams
Dimensions
220x150x14 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

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