The Dynamic Bacterial Genome: 8 (Advances in Molecular and Cellular Microbiology, Series Number 8)

Mullany, Peter

ISBN 10: 0521129613 / ISBN 13: 9780521129619

Published by Cambridge University Press, 2010

Most items will be dispatched the same or the next working day. A copy that has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged. Seller Inventory # wbs2850263203

Synopsis:

This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Genome rearrangements are a result of the actions of discrete genetic elements such as conjugative transposons, plasmids, phage, and non-conjugative transposons. Bacteria also contain systems to mediate genetic rearrangements such as the general recombination pathway and specialized endogenous recombination mechanisms. The biological effects of these rearrangements are far-reaching and impact on bacterial virulence, antibiotic resistance and the ability of bacteria to avoid the attentions of the host immune system (e.g. antigenic variation). These rearrangements also provide the raw material on which natural selection can act. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. This book is written by leading research workers and is an invaluable resource for graduate students and researchers in this field.

About the Author: Peter Mullany is a Reader in Molecular Microbiology at University College London. His main research interests are the molecular biology and molecular ecology of conjugative transposons. He has been at the forefront of this work for the past 10 years and has pioneered the genetic analysis of the important human pathogen Clostridium difficile.

Bibliographic Details

Title: The Dynamic Bacterial Genome: 8 (Advances in...
Publisher: Cambridge University Press
Publication Date: 2010
Binding: Soft cover
Condition: Very Good