Dual Drug Delivery System Containing Ornidazole and Ofloxacin

Language: English

Published by LAP LAMBERT Academic Publishing Feb 2015, 2015

3659396052 / 9783659396052

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes the design and evaluation of multiple unit pellet system (MUPS) for dual drug delivery i.e. sustained release ofloxacin and colon targeted ornidazole to treat dysentery as an alternative to conventional formulations. It involves a detailed procedural aspects for formulation and coating of pellets with Eudragit RS100 and Eudragit S100. It also describes an in vitro evaluation of pellets for various parameters along with in vivo colon targeting. The book describes the DOE approach for the Ofloxacin sustained release pellets optimization using full factorial design. It describes the modeling of dissolution kinetics. In vivo X-ray images showed similarity with in vitro release profile that pellets disappear only after reaching to colon. Multiple unit pellet system provided extended release of ofloxacin and delivery of ornidazole to colon providing an alternative for conventional formulations in treatment of amoebic dysentery with reduced side effects. Drug-excipient compatibility study revealed no interaction between drug and excipients. Optimized formulation showed good stability at accelerated environmental conditions. 108 pp. Englisch.…

Seller Inventory # 9783659396052

Title
Dual Drug Delivery System Containing Ornidazole and Ofloxacin
Author
Dasharath M. Patel
Publisher
LAP LAMBERT Academic Publishing Feb 2015
Publication year
2015
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659396052
ISBN 13
9783659396052
Item weight
179 grams
Dimensions
220x150x8 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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BuchWeltWeit Ludwig Meier e.K.

Germany