Dual Drug Delivery System Containing Ornidazole and Ofloxacin : Colon Targeted Ornidazole and Sustained Release Ofloxacin Pellets for Treatment of Amoebic Dysentery
Language: English
Published by LAP LAMBERT Academic Publishing, 2015
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 47.93
Quantity: 1 available
Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - This book describes the design and evaluation of multiple unit pellet system (MUPS) for dual drug delivery i.e. sustained release ofloxacin and colon targeted ornidazole to treat dysentery as an alternative to conventional formulations. It involves a detailed procedural aspects for formulation and coating of pellets with Eudragit RS100 and Eudragit S100. It also describes an in vitro evaluation of pellets for various parameters along with in vivo colon targeting. The book describes the DOE approach for the Ofloxacin sustained release pellets optimization using full factorial design. It describes the modeling of dissolution kinetics. In vivo X-ray images showed similarity with in vitro release profile that pellets disappear only after reaching to colon. Multiple unit pellet system provided extended release of ofloxacin and delivery of ornidazole to colon providing an alternative for conventional formulations in treatment of amoebic dysentery with reduced side effects. Drug-excipient compatibility study revealed no interaction between drug and excipients. Optimized formulation showed good stability at accelerated environmental conditions.…
Seller Inventory # 9783659396052
- Title
- Dual Drug Delivery System Containing Ornidazole and Ofloxacin : Colon Targeted Ornidazole and Sustained Release Ofloxacin Pellets for Treatment of Amoebic Dysentery
- Author
- Jignesh A. Soneji
- Publisher
- LAP LAMBERT Academic Publishing
- Publication year
- 2015
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3659396052
- ISBN 13
- 9783659396052
- Item weight
- 179 grams
- Dimensions
- 220x150x8 mm
"Synopsis" may belong to another edition of this title.
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| Item | 7 to 10 business days | 5 to 7 business days |
|---|---|---|
| First item | £ 29.67 | £ 38.14 |
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AHA-BUCH GmbH
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Einbeck, Germany 37574
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AHA-BUCH GmbH
represented by the managing director Christel Glass
Garlebsen 48
37574 Einbeck
Deutschland
Telefon: 055639996039
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E-Mail: abebooks@aha-buch.de
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