Drugs and the Developing Brain

Language: English

Published by Springer, Springer Feb 2012, 2012

1468430653 / 9781468430653

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This item is printed on demand - Print on Demand Titel. Neuware -The thalidomide tragedy which occurred slightly more than a decade ago made public officials and the general public acutely aware of the teratogenic potential of drugs. Although specialists in pharmacology and developmental biology had been studying this problem many years before, this catastrophic episode triggered the passage of legislation which required that information about the teratogenicity of drugs be produced before the drugs could be available to the general public. Gross deformities in man produced by drugs are frequently difficult to reproduce in experimental animals and the changes which are produced in other animals are frequently not translatable to humans. The problem of evaluating the potential that drugs have to produce gross malformations is small, however, compared to the evaluation of subtle but permanent behavioral effects which drugs may exert upon the developing organism. Nevertheless, many experimental studies in recent years indicate that subtle biochemical changes produced by drugs on brain tissue during critical periods of fetal or early post natal maturation may become manifest subsequently as behavioral deviations in early childhood or adolescence. Hyperkinetic disorders, epilepsies and other developmental disabilities may have a subtle biochemical imbalance, perhaps drug induced, as an underlying factor. This symposium was organized with the intent of bringing to gether prominent investigators who are working in different aspects of brain development and who are interested in the effects of drugs on the developing brain in order to discuss their findings, pro pose new theories, and open new avenues for future research.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 552 pp. Englisch.…

Seller Inventory # 9781468430653

Title
Drugs and the Developing Brain
Author
Antonia Vernadakis
Publisher
Springer, Springer Feb 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1468430653
ISBN 13
9781468430653
Item weight
1,025 grams
Dimensions
254x178x30 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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