Drug Selectivity
Language: English
Published by Wiley-VCH GmbH, 2018
- Hardcover
- New

Seller: moluna, Greven, Germanymoluna
AbeBooks seller since July 9, 2020
Condition: New
£ 160.59
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Add to basketItem description from seller
Seller Inventory # 201030121
- Title
- Drug Selectivity
- Author
- Handler, Norbert|Buschmann, Helmut|Buschmann, Helmut|Mannhold, Raimund|Holenz, Jörg
- Publisher
- Wiley-VCH GmbH
- Publication year
- 2018
- Condition
- New
- Binding
- Gebunden
- Language
- English
- ISBN 10
- 3527335382
- ISBN 13
- 9783527335381
- Dimensions
- 2.9 x 25.2 x 17.8
- Seller catalogs
- Mathematik/Naturwissenschaften/Technik/Medizin
The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.
"Synopsis" may belong to another edition of this title.
About the Author
Helmut Buschmann has a PhD in organic chemistry from Aachen University and extensive industrial experience in medicinal chemistry, drug discovery and development, scale-up, pharmaceutical development, CMC, patent filing and prosecution. Helmut has over 25 years of international experience in drug discovery research and drug development in the pharmaceutical/biotechnology sectors, both in industry and academia. During his career he worked with a broad range of different targets in different therapeutic areas from pain research to anti-infectives. He has a long publication and patent record, being an author/co-author in more than 150 scientific publications, editor of various reference books and is a named inventor/co-inventor in more than 250 patent applications.
As a result of his research activities more than 15 NCEs within different therapeutic areas have entered the clinical phase (e.g. Rosonabant, Cizorlitine, Dulopetine, Axamadol,). Some of them have reached clinical phase III or are marketed (e.g. Tapentadol: Nucynta® Palexia®). Currently, he is Head of Chemistry, Pharmaceutical Development and Patent A_ airs at AiCuris, Wuppertal and cofounder and co-owner of RD&C Research, Development & Consulting in Vienna.
"About the title" may belong to another edition of this title.
Shipping rates from Germany to U.S.A.
| Item | 13 to 40 business days | 13 to 40 business days |
|---|---|---|
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