Drug Discovery and Development

Language: English

Published by Humana Press, 2011

1461291801 / 9781461291800

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nach der Bestellung gedruckt Neuware - Printed after ordering - The conceptual process of drug discovery is one that is often the result of an identified need in a defined disease area. This need represents a mandate from the marketing department of a phar maceutical company or a breakthrough at the research level that has agreed applicability in response to a valid therapeutic demand. Although the intelligent design and development of new thera peutic entities, as evidenced by Sir James Black's H -receptor an 2 tagonist cimetidine (Tagamet), is intellectually satisfying, many novel drugs arise from serendipity, from the chance observation of the research scientist or the clinician, that a compound has unex pected actions of use for the treatment of human disease states. Drugs that have been identified by this route include the antipsy chotic chlorpromazine and the putative anxiolytic buspirone. The events surrounding the process of drug discovery and de velopment are the theme of the present volume, which attempts to present, in a logical and lucid manner, the complexity of a process that is often naively assumed to represent nothing more than the identification of a new compound and its rapid introduction into humans, free of such complications as efficacy, selectivity, safety, bioavailability, toxicity, and need.

Seller Inventory # 9781461291800

Title
Drug Discovery and Development
Author
Jeffrey B Malick
Publisher
Humana Press
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1461291801
ISBN 13
9781461291800
Item weight
703 grams
Dimensions
235x155x26 mm

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