Drug Designing:Homology modeling of PKC inhibitors
Language: English
Published by LAP LAMBERT Academic Publishing Sep 2012, 2012
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 42.12
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Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -Computer Aided Drug designing is the approach of finding new drugs, based on the biological targets (the protein). Protein kinase C (PKC) is an isozymes and a subclass of threonine/serine kinase family of proteins. it is known to be an important class of enzymes in cell signaling and as drug targets, cell cycle control has led to detailed structural and functional studies in various eukaryotes, and hence to the synthesis of specific chemical inhibitors for managing disease.Homology modeling of Protein kinase C delta predicts a 3-D structure protein.Homology models were generated by software tool called 'MODELLER'.Phosphorylation by protein kinases is a central theme in biological systems. Activity of protein kinases will be stopped by blocking the phosphorylation. ATP docking with protein kinase C is the main step in this research work and was successfully done. The results of ATP docking were compared with another protein in which ATP was already docked. Then inhibitors of protein kinase C delta were retrieved and converted into pdb file format, their docking with protein was also carried out by AutoDock Vina. 84 pp. Englisch.…
Seller Inventory # 9783659251399
- Title
- Drug Designing:Homology modeling of PKC inhibitors
- Author
- Waseem Akhtar Shamshari
- Publisher
- LAP LAMBERT Academic Publishing Sep 2012
- Publication year
- 2012
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3659251399
- ISBN 13
- 9783659251399
- Item weight
- 143 grams
- Dimensions
- 220x150x6 mm
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About the Author
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BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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