DiversityOriented Synthesis Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology
Language: English
Published by John Wiley & Sons Inc, 2013
- Hardcover
- New
Seller: Revaluation Books, Exeter, United KingdomRevaluation Books
AbeBooks seller since January 6, 2003
Condition: New
£ 190.96
Quantity: 2 available
Add to basketItem description from seller
1st edition. 664 pages. 9.30x5.70x1.50 inches. In Stock.
Seller Inventory # x-1118145658
- Title
- DiversityOriented Synthesis Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology
- Author
- Trabocchi, Andrea/ Schreiber, Stuart L. (Foreward By)
- Publisher
- John Wiley & Sons Inc
- Publication year
- 2013
- Condition
- Brand New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 1118145658
- ISBN 13
- 9781118145654
- Item weight
- 1.24 kilograms
Discover an enhanced synthetic approach to developing and screening chemical compound libraries
Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology.
Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book:
- Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles
- Expands on the concept of diversity-oriented synthesis by describing chemical libraries
- Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays
- Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research
This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications.
Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.
"Synopsis" may belong to another edition of this title.
About the Author
ANDREA TRABOCCHI, PhD, is Assistant Professor of Organic Chemistry at the University of Florence. Dr. Trabocchi leads research in diversity-oriented synthesis, peptidomimetic chem-istry, chemical genetics, and conformational analysis.
"About the title" may belong to another edition of this title.
Revaluation Books
Exeter, United Kingdom
AbeBooks seller since January 6, 2003
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Edward Bowditch Ltd
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Exeter, United Kingdom EX3 0PP
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