Diffusion-Reaction Modeling,Nonlinear Dynamics,Feedback,Bifurcation and Chaotic Behavior : of the Acetylcholine Neurocycle and their Relation to Alzheimer's and Parkinson's Diseases
Language: English
Published by Scholars' Press, 2018
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 78.49
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - The disturbances and abnormalities occurring in the components of the Acetylcholine (ACh) neurocycle are considered one of the main features of cholinergic sicknesses like Parkinson's and Alzheimer's diseases. A fundamental understanding of the ACh neurocycle is therefore very critical in order to design drugs that keep the ACh concentrations in the normal physiological range. In this dissertation, a novel two-enzyme-two-compartment model is proposed in order to explore the bifurcation, dynamics, and chaotic characteristics of the ACh neurocycle. The model takes into consideration the physiological events of the choline uptake into the presynaptic neuron and the ACh release in the postsynaptic neuron. In order to approach more realistic behavior, two complete kinetic mechanisms for enzymatic processes pH-dependent are built: the first mechanism is for the hydrolysis reaction catalyzed by the acetylcholinesterase (AChE) and the other is for the synthesis reaction catalyzed by the cholineacetyltransferase (ChAT).…
Seller Inventory # 9783639864205
- Title
- Diffusion-Reaction Modeling,Nonlinear Dynamics,Feedback,Bifurcation and Chaotic Behavior : of the Acetylcholine Neurocycle and their Relation to Alzheimer's and Parkinson's Diseases
- Author
- Ibrahim Mustafa
- Publisher
- Scholars' Press
- Publication year
- 2018
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3639864204
- ISBN 13
- 9783639864205
- Item weight
- 369 grams
- Dimensions
- 220x150x15 mm
"Synopsis" may belong to another edition of this title.
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