Diagnosing Developmental Dyscalculia on the Basis of Reliable Single Case FMRI Methods: Promises and Limitations Der Medizinischen Fakultät der RWTH Aachen vorgelegte Dissertation zur Erlangung des akad. Grades eines Doktors der Medizin

Published by Aachen, 2014

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Seller: Roland Antiquariat UG haftungsbeschränkt, Weinheim, GermanyRoland Antiquariat UG haftungsbeschränkt

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Softcover

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27 S. Cover with average soiling, pages in very good condition. --- FMRI-studies are mostly based on a group study approach, either analyzing one group or comparing multiple groups, or on approaches that correlate brain activation with clinically relevant criteria or behavioral measures. In this study we investigate the potential of fMRI-techniques focusing on individual differences in brain activation within a test-retest reliability context. We employ a single-case analysis approach, which contrasts dyscalculic children with a control group of typically developing children. In a second step, a support-vector machine analysis and cluster analysis techniques served to investigate similarities in multivariate brain activation patterns. Children were confronted with a non-symbolic number comparison and a non-symbolic exact calculation task during fMRI acquisition. Conventional second level group comparison analysis only showed small differences around the angular gyrus bilaterally and the left parieto-occipital sulcus. Analyses based on single-case statistical procedures revealed that developmental dyscalculia is characterized by individual differences predominantly in visual processing areas. Dyscalculic children seemed to compensate for relative under-activation in the primary visual cortex through an upregulation in higher visual areas. However, overlap in deviant activation was low for the dyscalculic children, indicating that developmental dyscalculia is a disorder characterized by heterogeneous brain activation differences. Using support vector machine analysis and cluster analysis, we tried to group dyscalculic and typically developing children according to brain activation. Fronto-parietal systems seem to qualify for a distinction between the two groups. However, this was only effective when reliable brain activations of both tasks were employed simultaneously. Results suggest that deficits in number representation in the visual-parietal cortex get compensated for through finger related aspects of number representation in fronto-parietal cortex. We conclude that dyscalculic children show large individual differences in brain activation patterns. Nonetheless, the majority of dyscalculic children can be differentiated from controls employing brain activation patterns when appropriate methods are used. Sprache: Englisch Gewicht in Gramm: 250.…

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Bibliographic details

Title
Diagnosing Developmental Dyscalculia on the Basis of Reliable Single Case FMRI Methods: Promises and Limitations Der Medizinischen Fakultät der RWTH Aachen vorgelegte Dissertation zur Erlangung des akad. Grades eines Doktors der Medizin
Author
Dinkel, Philipp:
Publisher
Aachen
Publication year
2014
Binding
Lex. 8° (25-30 cm), kart.
Seller catalogs
Medizin

Roland Antiquariat UG haftungsbeschränkt

Weinheim, Germany

5-star seller

AbeBooks seller since February 12, 2002

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Das Roland Antiquariat ist ein im Jahre 2001 gegründetes Versand-Antiquariat mit einem breiten Sortiment antiquarischer und seltener Bücher aus zahlreichen Gebieten. Schwerpunkte sind Fotobücher, Geschichte, Militärgeschichte, Kulturgeschichte,Philosophie, Orts- und Landeskunde sowie generell wissenschaftliche Literatur. Zur Erweiterung unseres Sortiments sind wir stets am Ankauf interessanter Einzelstücke sowie größerer Sammlungen zu einem Thema oder auch ganzer Bibliotheken, vorzugsweise wissenschaftlichen Inhalts, interessiert. Rufen Sie uns gerne an unter 06201-7303617 oder schreiben Sie eine mail an info@rolandantiquariat.de. Als Versandantiquariat führen wir kein Ladengeschäft mit festen Öffungszeiten, Besucher sind jedoch nach telefonischer Voranmeldung jederzeit willkommen.…

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Militärgeschichte, Philosophie, Theologie, Judaica, Photographie, Architektur, Geschichte

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Roland Antiquariat UG (haftungsbeschränkt)

Beundstraße 29
Weinheim, Germany 69469