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Developing Costimulatory Molecules for Immunotherapy of Diseases

Manzoor Ahmad Mir

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ISBN 10: 0128025859 / ISBN 13: 9780128025857
Published by Academic Press, 2015
New Condition: New Soft cover
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Bibliographic Details

Title: Developing Costimulatory Molecules for ...

Publisher: Academic Press

Publication Date: 2015

Binding: Paperback

Book Condition:New

Edition: 1.

About this title

Synopsis:

Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation. The text aims to provide the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families, with the hope that targeting these families will yield new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases.

Review:

"...a solid framework to understand costimulation and its role in selected diseases...best serves as a fundamental review of costimulation with clinical correlates for the basic-science researcher." --Annals of Allergy, Asthma & Immunology

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