Detection of some AML Fusion Genes by Molecular Biology Technique
Language: English
Published by LAP LAMBERT Academic Publishing Okt 2013, 2013
- Softcover
- New
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
AbeBooks seller since January 23, 2017
Condition: New
£ 43.15
Quantity: 1 available
Add to basketItem description from seller
This item is printed on demand - Print on Demand Titel. Neuware -The diagnosis, prognosis, and treatment of acute myeloid leukemia (AML) has been transformed over the past 15 years from a disease defined, classed, and staged based on histologic characteristics alone to a disease classified largely based on genetic, genomic, and molecular characteristics. The risk pattern in AML is determined not only by cytogenetic abnormalities, such as chromosomal deletions, duplications, or substitutions, but also by the elucidation of certain molecular mutations leading to over- or under-expressions of one of many proteins.This book was aimed to detect the three most frequently occurring reciprocal translocations of(AML) by reverse transcriptase polymerase chain reaction (RT-PCR): AML1-ETO associated with t(8;21), CBFB-MYH11 with inv(16), PML-RARA with t(15;17). The incidence of the common fusion transcripts in our pilot study is in accordance with that described in western studies. It is important to identify these transcripts as they provide useful prognostic information to the treating clinician.This study helps to establish the RT-PCR technique for the first time in the detection of these AML fusion genes,in the molecular biology department in Sudan.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 88 pp. Englisch.…
Seller Inventory # 9783659446818
- Title
- Detection of some AML Fusion Genes by Molecular Biology Technique
- Author
- Eman Abbass
- Publisher
- LAP LAMBERT Academic Publishing Okt 2013
- Publication year
- 2013
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3659446815
- ISBN 13
- 9783659446818
- Item weight
- 149 grams
- Dimensions
- 220x150x6 mm
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buchversandmimpf2000
Emtmannsberg, BAYE, Germany
AbeBooks seller since January 23, 2017
Shipping rates from Germany to U.S.A.
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