Design, Synthesis and Evaluation of Some Novel Heterocyclic Compounds

Language: English

Published by LAP LAMBERT Academic Publishing Apr 2016, 2016

3659873071 / 9783659873072

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This item is printed on demand - Print on Demand Titel. Neuware -In the present research work a new series of 1,3,4-oxadiazole & pyrazolone derivatives have been synthesized. 2-mercapto-1,3,4-oxadiazole derivatives were synthesized by reacting corresponding acid hydrazide with carbon disulfide followed by condensing the active hydrogen atom of 2-mercapto group of 5-aryl-2-mercapto-1,3,4-oxadiazole with 2-chloro pyridine, 4-chloro aniline & epichlorohydrine to give 5-aryl-2-(substituted aryl ylthio)-1,3,4-oxadiazole derivatives(A1-3, B1-4). 5-(substituted aryl)-1,3,4-oxadiazole derivatives were synthesized by reacting salicylic acid hydrazide with aromatic acid to give 5-(2-hydroxy phenyl)-2-aryl-1,3,4-oxadiazole derivatives (A4-6): 3-methyl-pyrazol-5(4H)-one derivatives were synthesized by reacting corresponding acid hydrazide with ethyl acetoacetate to give 1-(substituted aryl)-3-methyl-1H-pyrazol-5(4H)-one. Followed by condensing the active hydrogen atom of ¿CH2- of pyrazolone with Isonicotinic acid hydrazine/ p-amino salicylic acid/ sulfanilamide / 5-amino tetrazole / pyrazinoic acid hydrazide / 2-amino pyrazine to give corresponding pyrazolone derivatives (A7-11, B5-9).VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 84 pp. Englisch.…

Seller Inventory # 9783659873072

Title
Design, Synthesis and Evaluation of Some Novel Heterocyclic Compounds
Author
Parag Rabara
Publisher
LAP LAMBERT Academic Publishing Apr 2016
Publication year
2016
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659873071
ISBN 13
9783659873072
Item weight
143 grams
Dimensions
220x150x6 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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