Design of Sustained Release Tablet Using Melt Granulating Techniques

Language: English

Published by Scholars' Press Mrz 2021, 2021

6138933605 / 9786138933601

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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Item description from seller

This item is printed on demand - it takes 3-4 days longer - Neuware -Aceclofenac can be successfully designed in tablets as sustained release formulation using melt granulation technique. The present study has demonstrated that stearic acid could be successfully employed as a meltable binder. It is worthy of mentioning that for controlling the release of poorly water-soluble drugs, the method is still advantageous.The prepared Aceclofenac compressed tablets were tested for weight variation, content uniformity, friability, tablet thickness and drug content and all the parameters were found to be within the Pharmacopoeial limits. In vitro drug dissolution tests were performed and dissolution profile of the selected batch was matched with that of standard release profile suggested by USP. Hence, the formulation was selected as optimized formulation. The tablets were further evaluated for studying the effect of storage temperature and pH on drug release. The release profiles show no significant difference in drug releases. This confirms the prepared tablets were robust. 72 pp. Englisch.…

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Bibliographic details

Title
Design of Sustained Release Tablet Using Melt Granulating Techniques
Author
Suresh Sudke
Publisher
Scholars' Press Mrz 2021
Publication year
2021
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6138933605
ISBN 13
9786138933601
Item weight
125 grams
Dimensions
220x150x5 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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BuchWeltWeit Ludwig Meier e.K.

Germany