Design and Development of Colon Targeted Drug delivery System | A Novel Approach to target Colon

Mukesh R. Patel (u. a.)

ISBN 10: 3847309765 / ISBN 13: 9783847309765

Published by LAP Lambert Academic Publishing, 2012

Design and Development of Colon Targeted Drug delivery System | A Novel Approach to target Colon | Mukesh R. Patel (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783847309765 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 106423218

Synopsis:

The oral administration is the most convenient and commonly used method for drug delivery. Traditionally, solid oral dosage forms have been designed to release their drug load in the upper region of the gastrointestinal tract, where conditions are more suited to drug dissolutions and absorptions. Recently, greater emphasis has been placed on controlling site of drug release from oral formulations for the purposes of improving patient compliance and treatment efficiency . Many protein and peptide drugs like insulin cannot be administered through the oral route because of their degradation by the digestive enzymes of the stomach and the small intestine. Colon-specific drug delivery systems offer several potential therapeutic advantages.The opportunity to reduce adverse effects in the treatment of colonic diseases like, ulcerative colitis, colorectal cancer, Chorn’s diseases and amoebiasis by topical application of drugs, active at the mucosal level The elucidation of the mode of action of some nonsteroidal anti-inflammatory drugs (NSAIDs) such as sulindac (metabolized in the colon to the active moiety, sulindac sulfide) that were found to interfere with the proliferation of co

About the Author: DR. Mukesh R Patel did B.Pharm from N M University & M.Pharm From RajivGandhi University,and doctorate From H N GUniversity,Gujarat, India started his carrier as a Lecturer,Currently working as associate professor& Head in Pharmaceutical technology , BMCPER,Modasa, he has Published number of Research Papers in National and International journals.

Bibliographic Details

Title: Design and Development of Colon Targeted ...
Publisher: LAP Lambert Academic Publishing
Publication Date: 2012
Binding: Taschenbuch
Condition: Neu