Design And Development of Alfuzosin HCL Floating Microspheres Floating Microspheres of Alfuzosin HCl
Language: English
Published by LAP LAMBERT Academic Publishing, 2013
- Softcover
- New
Condition: New
£ 77.23
Quantity: 2 available
Add to basketItem description from seller
The purpose was to formulate Floating microspheres of Alfuzosin HCl, an orally administered alpha adrenergic blocker used to treat benign prostatic hyperplasia with a view of improving its oral bioavailability and giving a prolonged release of drug.Floating microspheres with biocompatible enteric acrylic polymer such as Eudragit S100 and cellulose polymers such as HPMC K100 M were successfully prepared by emulsion solvent evaporation method. The particle size analysis revealed that the size of microspheres was found to increase with increase in the concentration of polymer. In vitro drug release studies showed that the release of drug decreases with increases drug to polymer ration of microspheres. From the stability study it was found that there was no significant change in the physical appearance, drug entrapment, release characteristics and floating behavior of the microspheres. Sprache: Englisch Gewicht in Gramm: 292.
Seller Inventory # IB-7317620
Bibliographic details
- Title
- Design And Development of Alfuzosin HCL Floating Microspheres Floating Microspheres of Alfuzosin HCl
- Author
- Mukesh R. Patel, Megha Shah
- Publisher
- LAP LAMBERT Academic Publishing
- Publication year
- 2013
- Condition
- Neu
- Binding
- Softcover/Taschenbuch
- Language
- English
- ISBN 10
- 3659427888
- ISBN 13
- 9783659427886
- Item weight
- 292 grams
Shipping rates from Germany to U.S.A.
| Item | 10 to 12 business days | 8 to 10 business days |
|---|---|---|
| First item | £ 41.62 | £ 62.56 |
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