Design of Antidiabetics with the help of Modern Chemistry
Language: English
Published by LAP LAMBERT Academic Publishing Sep 2013, 2013
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 62.78
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -Increased incidence of type 2 diabetes mellitus and obesity has elevated the medical need for new agents to treat these disease states. Also dyslipidemia is connected with insulin insensitivity and associated to increased atherosclerosis susceptibility. Therefore, it would be added advantage in antidiabetic therapy, if any chemical entity takes care of diabetes as well as dyslipidemia. Resistance to the hormones insulin and leptin are hallmarks of both type 2 diabetes and obesity. Drugs that can ameliorate this resistance should be effective in treating type 2 diabetes and possibly obesity. Protein tyrosine phosphatase 1B (PTP1B) is thought to function as a negative regulator of insulin and leptin signal transduction.Hencesearch for new lead compound is significant requirement in this area. So, this work focus on molecular modeling studies tools like QSAR (2D&3D), ADME prediction and docking to design New chemical entities(NCE's). Synthesis of design NCE's and there protein tyrosine phosphatase 1B inhibition activity. 172 pp. Englisch.…
Seller Inventory # 9783659454769
- Title
- Design of Antidiabetics with the help of Modern Chemistry
- Author
- Rohan Bamane
- Publisher
- LAP LAMBERT Academic Publishing Sep 2013
- Publication year
- 2013
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3659454761
- ISBN 13
- 9783659454769
- Item weight
- 274 grams
- Dimensions
- 220x150x11 mm
"Synopsis" may belong to another edition of this title.
About the Author
"About the title" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
Shipping rates from Germany to U.S.A.
| Item | 5 to 15 business days | 5 to 15 business days |
|---|---|---|
| First item | £ 19.50 | £ 19.50 |
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BuchWeltWeit Ludwig Meier e.K.
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