Title: The Design and Analysis of Sequential Clinical Trials (Ellis Horwood Series in Mathematics and Its Applications)
Publisher: Horwood Publishing Limited
Publication Date: 1983
Language: English
ISBN 10: 0470273550
ISBN 13: 9780470273555
Binding: paperback
Condition: Very Good

About this title

Synopsis

This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include –spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.

Review

"...This book is clear, it provides many details and is well written..." (Statistical Methods in Medical Research, No.11, 2002)

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