Design and Analysis of DNA Microarray Investigations

Language: English

Published by Humana, 2004

0387001352 / 9780387001357

Series: Book 10 of 69 - Statistics for Biology and Health

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - DNA microarrays are an important technology for studying gene expression. With a single hybridization, the level of expression of thousands of genes, or even an entire genome, can be estimated for a sample of cells. Consequently, manylaboratoriesareattemptingtoutilizeDNAmicroarraysintheirresearch. Whereaslaboratoriesarewellpreparedtoaddressthesigni cantexperimental challenges in obtaining reproducible data from this RNA-based assay, inv- tigators are less prepared to analyze the large volumes of data produced by DNA microarrays. Although many software packages have been developed for the analysis of DNA microarray data, software alone is insu cient. One needs knowledge aboutthevariousaspectsofdataanalysisinordertoselectandutilizesoftware e ectively. There is a plethora of analysis methods being published and it is di cult for biologists to determine which methods are valid and appropriate for their problems. Many scientists have learned that software is not an adequate substitute for biostatistical knowledge and seek statistical collaborators. Unfortunately, there is presently a shortage of statisticians who are available and knowled- able about DNA microarrays. For statisticians to be e ective collaborators in anyarea,theymustinvestthetimetounderstandthesubjectmatterareaand become familiar with the literature so that they can ask the right questions and identify the key issues. Our objectives in this book are twofold: to provide scientists with infor- tion about the design and analysis of studies using DNA microarrays that will enable them to plan and analyze their own studies or to work with statistical collaborators e ectively, and to aid statistical and computational scientists wishing to develop expertise in this area.

Seller Inventory # 9780387001357

Title
Design and Analysis of DNA Microarray Investigations
Author
Michael D. Radmacher
Publisher
Humana
Publication year
2004
Condition
Neu
Binding
Buch
Language
English
ISBN 10
0387001352
ISBN 13
9780387001357
Item weight
560 grams
Dimensions
241x160x19 mm
Series
Book 10 of 69: Statistics for Biology and Health

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

Item5 to 7 business days7 to 10 business days
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