Decoding Darkness: The Search for the Genetic Causes of Alzheimer's Disease
Tanzi, Rudolph E.; Parson, Ann B.; Parson, Ann E.
Language: English
Published by Perseus Books Group, Scranton, Pennsylvania, U.S.A., 2000
- Hardcover
- Used
Seller: The Yard Sale Store, Narrowsburg, NY, U.S.A.The Yard Sale Store
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Condition: Used - Good
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Add to basketItem description from seller
PRESENTABLE hard covered edition in a FULL DUST JACKET. Slight scuff to the covers and page edge. USEFUL.
Seller Inventory # DJkHCNov16VI37
- Title
- Decoding Darkness: The Search for the Genetic Causes of Alzheimer's Disease
- Author
- Tanzi, Rudolph E.; Parson, Ann B.; Parson, Ann E.
- Publisher
- Perseus Books Group, Scranton, Pennsylvania, U.S.A.
- Publication year
- 2000
- Condition
- Good
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0738201952
- ISBN 13
- 9780738201955
"Synopsis" may belong to another edition of this title.
Review
Despite its ubiquity, the malady was, until recently, considered a "backwater disease" to which little research attention (and funding) was paid. Advances in gene research, some spearheaded by neurologist Rudolph Tanzi, have led to a new understanding of the causes of Alzheimer's disease, and new possibilities for its cure. In this well-written account of that research, Tanzi and journalist co-author Ann Parson examine the role of amyloid neuritic plaque, "mucked-up, misfolded protein that fibrilises and forms rock-hard aggregates that the body can't get rid of". This plaque occurs in humans and certain other carnivorous species (including bears and dogs), and it appears to play a role in neurological disorders of several kinds. Tanzi reports on recent studies in the use of cholesterol-reducing drugs in lessening levels of "brain dirt," as well as on research that suggests that cardiovascular exercise and a diet low in animal fats can benefit the brain as well as the body. He even cautiously hints that the conquest of Alzheimer's may occur in the very near future. For the time being, his book provides a thoughtful portrait of the illness and of the scholars and scientists who have devoted their lives to combating it. --Gregory McNamee
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