Decellularized Extracellular Matrix: Characterization, Fabrication and Applications (Biomaterials Science Series, Volume 6)

Tetsuji Yamaoka

ISBN 10: 1788014677 / ISBN 13: 9781788014670

Published by Royal Society of Chemistry, 2019

Seller Inventory # 9781788014670

Synopsis:

Using this book, the reader will gain a good foundation to the field complemented with a broad overview of characterisation, microfabrication and applications.

From the Back Cover:

The extracellular matrix (ECM) supports cells and regulates various cellular functions in our body. The native ECM promises to provide an excellent scaffold for regenerative medicine. In order to use the ECM as a scaffold in medicine, its cellular fractions need to be removed while retaining its structural and compositional properties. This process is called decellularization, and the resulting product is known as the decellularized extracellular matrix (dECM).

This book focuses on the sources of dECM and its preparation, characterization techniques, fabrication, and applications in regenerative medicine and biological studies. Using this book, the reader will gain a good foundation in the field of ECM decellularization complemented with a broad overview of dECM characterization, ranging from structural observation and compositional assessment to immune responses against dECM and applications, ranging from microfabrication and 3D-printing to the application of tissue-derived dECM in vascular grafts and corneal tissue engineering etc. The book closes with a section dedicated to cultured cell dECM, a complementary technique of tissue-derived dECM preparation, for application in tissue engineering and regenerative medicine, addressing its use in stem cell differentiation and how it can help in the study of the tumor microenvironment as well as in clinical trials of peripheral nerve regeneration.

Bibliographic Details

Title: Decellularized Extracellular Matrix: ...
Publisher: Royal Society of Chemistry
Publication Date: 2019
Binding: Hardcover
Condition: New