This book guides practitioners in the assessment of patients with a liver problem. The emphasis is on the role of macro- and microscopic pathology in elucidating pathogenesis as well as identifying confounding features of image findings that may lead to a more elaborate differential diagnosis. If appropriate, the role of light and electron microscopic examination, along with the role of specific stains and molecular techniques, is illustrated. In addition, the concept of each liver disease is summarized briefly and its up-to-data is provided, and unresolved problems in diagnosis, treatment, and pathogenesis are clearly described.
The approach in this book is a practical one with a focus on the evaluation of illustrative cases, simultaneously demonstrating cross-sectional images (ultrasonography, computed tomography, magnetic resonance imaging, and angiography), pathological findings, and peritoneoscopic images. The diagnosis and therapy are summed up in helpful tables, and association of clinical manifestations with image analysis and pathological findings is shown to be important in differential diagnosis and treatment. With the authors comprising internationally renowned experts, this book will serve as a useful source of information for medical students, physicians, internists, hepatologists, gastroenterologists, radiologists, and pathologists worldwide.
Dr. Etsuko Hashimoto is a Professor of Hepatology and Gastroenterology at Tokyo Women’s Medical University. She received her MD from Tokyo Women’s Medical University. She had the privilege of studying liver pathology under Professor Ludwig, who is a renowned pathologist at MAYO Clinic, from 1987 to 1991. Professor Ludwig is well known as he established the concepts and the definition of NASH. She has served on numerous committees for national and international societies including the Asia–Pacific Working Party on NAFLD. She is the author of the recent Japanese and Asia Practice Guideline for NAFLD/NASH. At present, her primary area of interest is in the field of NASH, specifically in elucidation of the characteristics of HCC in NASH. She has won multiple awards, both at the university, local, and national level.
Dr. Kwo is currently Professor of Medicine and Director of Hepatology at the Stanford University where he joined the faculty in November 2016. Prior to joining the faculty at Stanford, he was at Indiana University for 21 years where he served as the Medical Director of Liver Transplantation. He received his MD from Wayne State University School of Medicine, his Internal Medicine training at University of Maryland, and his Gastroenterology/Hepatology training at Mayo Clinic Rochester. He has served on numerous committees for national and international societies including the Nominating Committee and Clinical Research Committee for the AASLD and is Trustee for the ACG. He has distinguished himself in the field of chronic Hepatitis C and has served as the PI for multiple seminal trials in the treatment of hepatitis C. He is the author of the recent ACG Practice Guideline Evaluation of Abnormal Liver Chemistries. He has won multiple awards, both at the university, local, and national level.
Dr. Arief Suriawinata is a Professor of Pathology and Laboratory Medicine at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA. He received his medical doctor degree from University Indonesia, followed by residency in pathology at The Mount Sinai Hospital, New York, New York and fellowships in oncologic pathology and gastrointestinal pathology at Memorial Sloan Kettering Cancer Center, New York, New York. Dr. Suriawinata’s research interests include liver and pancreatobiliary malignancy and gastrointestinal diseases. He is a member of Laennec International Liver Pathology Society. Dr. Suriawinata is board certified in Anatomic and Clinical Pathology and Clinical Informatics.
Dr. Tsui graduated from the University of Hong Kong. After receiving training in Queen Elizabeth Hospital, HK, and Royal Free Hospital, UK, he was appointed Consultant Pathologist in Caritas Medical Centre and then the Director of the pathology department. He is a Past President of the Hong Kong Division of the International Academy of Pathology and a member of the Elves International Liver Pathology Study Group. His main academic interest is in hepatobiliary and gastrointestinal pathology. He has edited a liver pathology book, and published over 60 peer-reviewed articles and over 30 book chapters.
Dr. Iwai is currently Director in Iwai Clinic, Division of Gastroenterology, Hepatology and Internal Medicine. Prior to the Director he was at Kyoto Prefectural University School of Medicine, Department of Gastronenterology and Hepatology for 38 years where he served as an associated Professor. He received his MD from Kyoto Prefectural University School of Medicine, and clinical practice for Internal Medicine, Gastroenterology and Hepatology was trained in University, Municipal and Red Cross Hospital. His PhD was endowed by clarifying biological significane of AFP-positive cells in hepatocarcinogenesis in 1983 while he investigated protein-synthesis in liver of pathological conditions, relationship of HBV with hepatoma, roles of hepatic junctional complex for development or malignant transformation of hepatoma cells and gene therapy for hepatoma. He has distinguished himself in the field of autoimmune liver diseases and malignant tumors in liver. He was a member of AASLD and IASLD and served as a committee or board director in internal Conference of Gastroenterology and Hepatology. He won awards from national Society of Hepatology, local goverment and foundation and got budget for research at local and national level.
