Cytokines and Joint Injury

Language: English

Published by Birkh?user, 2004

3764370017 / 9783764370015

Series: Book 21 of 50 - Progress in Inflammation Research

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The purpose of this volume in the Progress in Inflammation Research series is to provide the biomedical and clinical researcher with a state-of-the-art insight in the role of cytokines in joint inflammation and joint destruction. This is of relevance for better understanding of key processes in diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Apart from the impact of old and novel cytokines on joint tissues, the various chapters address the issue of targeted therapy with biological response modifiers and future interventions with carefully designed inhibitors. Spe cial attention is given to elements of synovial cell activation, cell-cell interaction, cytokine interplay as well as mechanisms of cartilage destruction and bone erosion. In addition to an outline of the role of established cytokines, such as TNF, IL-l and IL-6, new information is given on the novel cytokines IL-15, IL-17 and IL-18 and their positioning in the complex cytokine interplay. Cytokine regulation of destructive enzymes, RANKL, the endogenous inhibitor OPG and their crucial roles as central players in joint erosion are highlighted. Together, the chapters provide a complete and balanced view on pivotal cytokines and joint pathology. Sprache: Englisch Gewicht in Gramm: 583.…

Title
Cytokines and Joint Injury
Publisher
Birkh?user
Publication year
2004
Condition
Neu
Binding
Gebundene Ausgabe
Language
English
ISBN 10
3764370017
ISBN 13
9783764370015
Item weight
583 grams
Series
Book 21 of 50: Progress in Inflammation Research

Home-set

Mannheim, Germany

5-star seller

AbeBooks seller since April 13, 2026

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Home-set

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