Current Perspectives in microRNAs (miRNA)

Language: English

Published by Springer, Springer Okt 2010, 2010

9048179033 / 9789048179039

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This item is printed on demand - Print on Demand Titel. Neuware -Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17¿25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native miRNA species found in vertebrates and many more new miRNA homologs continue to be identified; however, most of their functions remain to be determined. In this book, many new perspectives of the miRNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of miRNAs but also offer a great opportunity in developing new therapeutic interventions.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 472 pp. Englisch.…

Seller Inventory # 9789048179039

Title
Current Perspectives in microRNAs (miRNA)
Author
Shao-Yao Ying
Publisher
Springer, Springer Okt 2010
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
9048179033
ISBN 13
9789048179039
Item weight
709 grams
Dimensions
235x155x26 mm

buchversandmimpf2000

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