Cullin-RING Ligases and Protein Neddylation
Book 472 of 544: Advances in Experimental Medicine and BiologySun, Yi|Wei, Wenyi|Jin, Jianping
New - Hardcover
Condition: New
Ships from Germany to U.S.A.
Quantity: Over 20 available
Add to basketCondition: New
Quantity: Over 20 available
Add to basketDieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Summarizes all the important aspects of CRLsProvides potential strategies for targeting various human diseasesWritten by pioneers in the field of ubiquitin and neddylationDr. Yi Sun.
Seller Inventory # 319502998
Dr. Yi Sun completed his medical training in China in the early 1980s, his Ph.D. at the University of Iowa, USA, in 1989, and his postdoctorate at the NCI. Currently, he is a Lawrence-Krause Research Professor of Radiation Oncology, and Director of the Division of Radiation & Cancer Biology, Department of Radiation Oncology at the University of Michigan. His main research aims are validating SAG-Cullin RING Ligase (CRL) and neddylation as cancer targets, and identifying small molecule inhibitors against these targets for anticancer therapy. Dr. Sun is the author of 222 peer- reviewed articles published in various prestigious journals, including Dev Cell, eLife, J Cell Biol, J Clin Invest,Mol Cell,Nature Communications, PNAS, and Cancer Res. He serves as editorial board member of several scientific journals. He was elected as a fellow of the AAAS (American Association for the Advancement of Science) in 2012.
Dr. Wenyi Wei received his B.A. degree from Shandong University in 1993 and pursued his M.S. at the Chinese Academy of Science from 1993 to 1996. Afterwards, Dr. Wei completed his Ph.D. at the MCB department at Brown University and his postdoctorate at the laboratory of Dr. William Kaelin, Jr. at DFCI, Harvard Medical School. In 2006, Dr. Wei moved to the Department Pathology at Beth Israel Deaconess Medical Center, Harvard Medical School, where his research focuses on understanding how aberrant cell signaling events contribute to cell cycle dysregulation and subsequent tumorigenesis, to provide the molecular basis and the rationale to develop novel anti-cancer therapies targeting specific cell signaling pathways.
Dr. Jianping Jin completed his PhD at Texas A&M University at College Station in 2000, and his postdoctorate in Dr. J Wade Harper’s Laboratory at Baylor College of Medicine and then at Harvard Medical School. Currently, he is a Professor and senior investigatorat the Life Science Institute, Zhejiang University, China. His main research projects focus on the ubiquitin signaling pathway, and its roles in cancer and inflammation. He discovered Uba6, the second ubiquitin E1 gene (humans only have two ubiquitin E1 genes), and its specific E2 gene, Use1 (also called Ube2Z). He was among the first to identify the family of DCAF genes, which are substarte adaptors of the Cullin4 ubiquitin ligases. Dr. Jin has published more than 50 peer-reviewed articles, and serves as an editorial member of the Journal of Biological Chemistry. He was a co-organizer for three Cold Spring Harbor Asia meetings on the ubiquitin family.
"About this title" may belong to another edition of this title.
Instructions for revocation/
Standard Business Terms and customer information/ data protection declaration
Revocation right for consumers
(A ?consumer? is any natural person who concludes a legal transaction which, to an overwhelming extent, cannot be attributed to either his commercial or independent professional activities.)
Instructions for revocation
Revocation right
You have the right to revoke this contract within one month without specifying any reasons.
The revocation period is one month...
If you are a consumer you can withdraw from the contract in accordance with the following. Consumer means any natural person who is acting for purposes which are outside his trade, business, craft or profession.
Information regarding the right of withdrawal
Statutory right to withdraw
You have the right to withdraw from this contract within 14 days without giving any reason.
The withdrawal period will expire after 14 days from the day on which you acquire, or a third party other than the carrier and indicated by you acquires, physical possession of the last good or the last lot or piece.
To exercise the right of withdrawal, electronically fill in and submit a clear statement on our website, under "My Purchases" in "My Account". We will communicate to you an acknowledgement of receipt of such a withdrawal on a durable medium (e.g. by e-mail) without delay.
To meet the withdrawal deadline, it is sufficient for you to send your communication concerning your exercise of the right of withdrawal before the withdrawal period has expired.
Effects of withdrawal
If you withdraw from this contract, we will reimburse to you all payments received from you, including the costs of delivery (except for the supplementary costs arising if you chose a type of delivery other than the least expensive type of standard delivery offered by us).
We may make a deduction from the reimbursement for loss in value of any goods supplied, if the loss is the result of unnecessary handling by you.
We will make the reimbursement without undue delay, and not later than 14 days after the day on which we are informed about your decision to withdraw from this contract.
We will make the reimbursement using the same means of payment as you used for the initial transaction, unless you have expressly agreed otherwise; in any event, you will not incur any fees as a result of such reimbursement.
We may withhold reimbursement until we have received the goods back, or you have supplied evidence of having sent back the goods, whichever is the earliest.
You shall send back the goods or hand them over to moluna, Greven, Germany, without undue delay and in any event not later than 14 days from the day on which you communicate your withdrawal from this contract to us. The deadline is met if you send back the goods before the period of 14 days has expired. You will have to bear the direct cost of returning the goods. You are only liable for any diminished value of the goods resulting from the handling other than what is necessary to establish the nature, characteristics and functioning of the goods.
Exceptions to the right of withdrawal
The right of withdrawal does not apply to:
II. Kundeninformationen
Moluna GmbH
Engberdingdamm 27
48268 Greven
Deutschland
Telefon: 02571/5698933
E-Mail: abe@moluna.de
Wir sind nicht bereit und nicht verpflichtet, an Streitbeilegungsverfahren vor Verbraucherschlichtungsstellen teilzunehmen.
Die technischen Schritte zum Vertragsschluss, der Vertragsschluss selbst und die Korrekturmöglichkeiten erfolgen nach Maßgabe der Regelungen "Zustandekommen des Vertrages" unserer Allgemeinen Geschäftsbedingungen (Teil I.).
3.1. Vertragssprache ist deutsch .
3.2. Der vollständige Vertragstext wird von uns nicht gespeichert. Vor Absenden der Bestellung können die Vertragsdaten über die Druckfunktion des Browsers ausgedruckt oder elektronisch gesichert werden. Nach Zugang der Bestellung bei uns werden die Bestelldaten, die gesetzlich vorgeschriebenen Informationen bei Fernabsatzverträgen und die Allgemeinen Geschäftsbedingungen nochmals per E-Mail an Sie übersandt.
Die wesentlichen Merkmale der Ware und/oder Dienstleistung finden sich im jeweiligen Angebot.
5.1. Die in den jeweiligen Angeboten angeführten Preise sowie die Versandkosten stellen Gesamtpreise dar. Sie beinhalten alle Preisbestandteile einschließlich aller anfallenden Steuern.
5.2. Die anfallenden Versandkosten sind nicht im Kaufpreis enthalten. Sie sind über eine entsprechend bezeichnete Schaltfläche auf unserer Internetpräsenz oder im jeweiligen Angebot aufrufbar, werden im Laufe des Bestellvorganges gesondert ausgewiesen und sind von Ihnen zusätzlich zu tragen, soweit nicht die versandkostenfreie Lieferung zugesagt ist.
5.3. Die Ihnen zur Verfügung stehenden Zahlungsarten sind unter einer entsprechend bezeichneten Schaltfläche auf unserer Internetpräsenz oder im jeweiligen Angebot ausgewiesen.
5.4. Soweit bei den einzelnen Zahlungsarten nicht anders angegeben, sind die Zahlungsansprüche aus dem geschlossenen Vertrag sofort zur Zahlung fällig.
6.1. Die Lieferbedingungen, der Liefertermin sowie gegebenenfalls bestehende Lieferbeschränkungen finden sich unter einer entsprechend bezeichneten Schaltfläche auf unserer Internetpräsenz oder im jeweiligen Angebot.
Soweit im jeweiligen Angebot oder unter der entsprechend bezeichneten Schaltfläche keine andere Frist angegeben ist, erfolgt die Lieferung der Ware innerhalb von 3-5 Tagen nach Vertragsschluss (bei vereinbarter Vorauszahlung jedoch erst nach dem Zeitpunkt Ihrer Zahlungsanweisung).
6.2. Soweit Sie Verbraucher sind ist gesetzlich geregelt, dass die Gefahr des zufälligen Untergangs und der zufälligen Verschlechterung der verkauften Sache während der Versendung erst mit der Übergabe der Ware an Sie übergeht, unabhängig davon, ob die Versendung versichert oder unversichert erfolgt. Dies gilt nicht, wenn Sie eigenständig ein nicht vom Unternehmer benanntes Transportunternehmen oder eine sonst zur Ausführung der Versendung bestimmte Person beauftragt haben.
Sind Sie Unternehmer, erfolgt die Lieferung und Versendung auf Ihre Gefahr.
Die Mängelhaftung richtet sich nach der Regelung "Gewährleistung" in unseren Allgemeinen Geschäftsbedingungen (Teil I).
letzte Aktualisierung: 23.10.2019
| Order quantity | 26 to 60 business days | 26 to 60 business days |
|---|---|---|
| First item | £ 42.37 | £ 42.37 |
Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.