Colorectal Cancer Diagnosis: Advancements and Applications

This book highlights the potential applications of microbots for minimally invasive diagnosis of colorectal cancer (CRC), enhancing the accuracy of colonoscopy and improving drug delivery for more precise and effective treatments. The introductory chapter explores advanced CRC diagnostic and therapeutic approaches, from understanding the disease’s prevalence to assessing the limitations of invasive techniques. It further discusses non-invasive screening methods and state-of-the-art imaging technologies, paving the way for less intrusive and more accessible diagnostics. The book, in turn, reviews techniques to tailor microbots for specifically targeting cancer cells effectively and provides a comparative analysis with nanobots for their potential in cancer diagnostics and therapeutics. It explores the intersection of photodynamic therapy and microrobotic technology, shedding light on the future of cancer therapy. With a focus on clinical translation, this book provides insight into the future application of mobile microrobots in medical imaging and in vivo perspectives of colorectal cancer, ultimately addressing the broader applications of bio-nanotechnology and microrobots in the realm of gastrointestinal diseases and cancer. This book is intended for researchers, students, and academicians in the fields of oncology, nanotechnology, and medical sciences.

Key Features

• Explores the latest advancements in microbot applications in diagnosis and drug delivery in colorectal cancer
• Offers a comprehensive examination of colorectal cancer diagnostics, ranging from traditional colonoscopies to advanced imaging technologies
• Presents practical applications and the potential for clinical translation of microbots in diagnosing and treating colorectal cancer
• Examines the potential use of mobile microrobots in medical imaging and offers in vivo perspectives on colorectal cancer
• Discusses techniques for customizing microbots to effectively target cancer cells and provides a comparative analysis with nanobots

Dr. Surajit Pathak is currently working as a Professor at Chettinad Academy of Research and Education, Kelambakkam, Chennai. He received his Ph.D. in Zoology from the University of Kalyani, West Bengal, India, in 2007 and completed his post-doctoral training at the University of Linkoping, Sweden; the University of Padova, Italy; and the University of Alabama, USA. His current research focuses on cancer biology, stem cell biology, regenerative medicine, and microRNA. He has published more than 60 research articles in peer-reviewed journals and has received various research grants, including core research grants from SERB (DST) and DST Indo-Italy Bi-lateral research projects. He is an editorial board member of various respected journals.

Dr. Antara Banerjee is currently working as an Associate Professor at the Chettinad Academy of Research and Education, Kelambakkam, Chennai. Antara Banerjee completed her PhD in 2008 and pursued her post-doctoral research at the University of Padova, Italy, till 2012. Later, she joined as a senior research associate at the University of Linkoping, Sweden, until 2015. She has published more than 50 impactful peer-reviewed articles in International and National Journals. Her core expertise is in stem cell biology, regenerative medicine, and oncology. She has received numerous awards, including the DST SERB and ECR awards from the Government of India for the period 2018–2021.