Chromosomal Translocations and Genome Rearrangements in Cancer
Language: English
Published by Springer Dez 2015, 2015
- Hardcover
- New
Seller: Books-by-Floh, Paderborn, GermanyBooks-by-Floh
AbeBooks seller since March 13, 2026
Condition: New
£ 207.91
Quantity: 2 available
Add to basketItem description from seller
Neuware -This volume collates world experts' insights into the molecular biology of cancer chromosomes, their abnormalities and the subsequent cellular consequences. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and somatic mutations, this book is a review of the field of cancer genetics that presages a new era, as whole genome sequencing becomes more accessible.The work begins with a look at historical themes, such as the analysis of metaphase chromosomes using microscopy and staining techniques, advances in which provided our first broad glimpse into the genetic anatomy of a malignant cell. Readers will learn about the application of DNA molecular cloning techniques in the 1980s, that led to the identification of the genes involved in the Philadelphia and Burkitt's lymphoma chromosomal translocations, solidifying the role of oncogenes and tumour suppressor genes in cancer aetiology via chromosomal alterations and which launched a field in cancer genetics.Subsequent chapters bring the reader up to date by reviewing recent developments in the field, with dedicated sections on leukaemia/lymphoma, sarcomas and epithelial tumours.Contributions feature numerous colour tables and illustrations and this volume will provide a basis for understanding cancer chromosomes for many years to come. 500 pp. Englisch.…
Seller Inventory # 9783319199825
- Title
- Chromosomal Translocations and Genome Rearrangements in Cancer
- Author
- Michelle M. Le Beau
- Publisher
- Springer Dez 2015
- Publication year
- 2015
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 331919982X
- ISBN 13
- 9783319199825
- Item weight
- 949 grams
- Dimensions
- 241x160x31 mm
This volume collates world experts’ insights into the molecular biology of cancer chromosomes, their abnormalities and the subsequent cellular consequences. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and somatic mutations, this book is a review of the field of cancer genetics that presages a new era, as whole genome sequencing becomes more accessible.
The work begins with a look at historical themes, such as the analysis of metaphase chromosomes using microscopy and staining techniques, advances in which provided our first broad glimpse into the genetic anatomy of a malignant cell. Readers will learn about the application of DNA molecular cloning techniques in the 1980s, that led to the identification of the genes involved in the Philadelphia and Burkitt's lymphoma chromosomal translocations, solidifying the role of oncogenes and tumour suppressor genes in cancer aetiology via chromosomal alterations and which launched a field in cancer genetics.
Subsequent chapters bring the reader up to date by reviewing recent developments in the field, with dedicated sections on leukaemia/lymphoma, sarcomas and epithelial tumours.
Contributions feature numerous colour tables and illustrations and this volume will provide a basis for understanding cancer chromosomes for many years to come.
"Synopsis" may belong to another edition of this title.
From the Back Cover
This volume collates world experts’ insights into the molecular biology of cancer chromosomes, their abnormalities and the subsequent cellular consequences. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and somatic mutations, this book is a review of the field of cancer genetics that presages a new era, as whole genome sequencing becomes more accessible.
The work begins with a look at historical themes, such as the analysis of metaphase chromosomes using microscopy and staining techniques, advances in which provided our first broad glimpse into the genetic anatomy of a malignant cell. Readers will learn about the application of DNA molecular cloning techniques in the 1980s, that led to the identification of the genes involved in the Philadelphia and Burkitt's lymphoma chromosomal translocations, solidifying the role of oncogenes and tumour suppressor genes in cancer aetiology via chromosomal alterations, and which launched a field in cancer genetics.
Subsequent chapters bring the reader up to date by reviewing recent developments in the field, with dedicated sections on leukaemia/lymphoma, sarcomas and epithelial tumours.
Contributions feature numerous colour tables and illustrations and this volume will provide a basis for understanding cancer chromosomes for many years to come.
"About the title" may belong to another edition of this title.
Books-by-Floh
Paderborn, Germany
AbeBooks seller since March 13, 2026
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Books-by-Floh steht für ein breites, kuratiertes Buchsortiment aus einer Hand. Unser Fokus liegt auf Qualität, Vielfalt und zuverlässiger Abwicklung.
Wir führen Romane, Krimis, Thriller, Liebesromane, Lyrik, Anthologien, Mythologie, Fachbücher sowie Werke der Gegenwartsliteratur – für Leserinnen und Leser mit Anspruch.
Alle Artikel werden ausschließlich aus Deutschland versendet. Das garantiert kurze Lieferzeiten, transparente Prozesse und einen verlässlichen Service.
Unser Anspruch: unkomplizierter Einkauf, Bücher, die man gerne liest – heute und morgen.
Books-by-Floh – Bücher. Klar. Verlässlich.
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