Chromatin and Epigenetics

Language: English

Published by Intechopen, 2020

1789844924 / 9781789844924

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Genomics has gathered broad public attention since Lamarck put forward his top-down hypothesis of 'motivated change' in 1809 in his famous book 'Philosophie Zoologique' and even more so since Darwin published his famous bottom-up theory of natural selection in 'The Origin of Species' in 1859. The public awareness culminated in the much anticipated race to decipher the sequence of the human genome in 2002. Over all those years, it has become apparent that genomic DNA is compacted into chromatin with a dedicated 3D higher-order organization and dynamics, and that on each structural level epigenetic modifications exist. The book 'Chromatin and Epigenetics' addresses current issues in the fields of epigenetics and chromatin ranging from more theoretical overviews in the first four chapters to much more detailed methodologies and insights into diagnostics and treatments in the following chapters. The chapters illustrate in their depth and breadth that genetic information is stored on all structural and dynamical levels within the nucleus with corresponding modifications of functional relevance. Thus, only an integrative systems approach allows to understand, treat, and manipulate the holistic interplay of genotype and phenotype creating functional genomes. The book chapters therefore contribute to this general perspective, not only opening opportunities for a true universal view on genetic information but also being key for a general understanding of genomes, their function, as well as life and evolution in general.…

Seller Inventory # 9781789844924

Title
Chromatin and Epigenetics
Author
Colin Logie
Publisher
Intechopen
Publication year
2020
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1789844924
ISBN 13
9781789844924
Item weight
850 grams
Dimensions
266x185x25 mm

AHA-BUCH GmbH

Einbeck, Germany

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