Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells
Language: English
Published by Springer US, Humana Mai 1990, 1990
- Hardcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 184.60
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability( CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. 448 pp. Englisch.…
Seller Inventory # 9780306434266
- Title
- Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells
- Author
- John M. Russell
- Publisher
- Springer US, Humana Mai 1990
- Publication year
- 1990
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 0306434261
- ISBN 13
- 9780306434266
- Item weight
- 1,034 grams
- Dimensions
- 260x183x29 mm
"Synopsis" may belong to another edition of this title.
Synopsis
"About the title" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
Shipping rates from Germany to U.S.A.
| Item | 5 to 15 business days | 5 to 15 business days |
|---|---|---|
| First item | £ 19.26 | £ 19.26 |
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BuchWeltWeit Ludwig Meier e.K.
Germany
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