Characterization of Peroxynitrite modified Glycated DNA

Language: English

Published by LAP Lambert Academic Publishing Dez 2016, 2016

3330014210 / 9783330014213

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -Glycation is the non-enzymatic addition or insertion of sugar molecules into DNA, protein and lipids that occur in biological molecules. The glycation of DNA give rise to characteristic nucleotide adducts, some of which have been found to increase in oxidative stress . The glycation causes damage to DNA which is associated with mutagenesis, carcinogenesis and is also considered to be a pathogenic factor for Diabetes mellitus. Improved understanding of DNA glycation may give guidance on decreasing the risk of tumor associated with dietary factors.Peroxynitrite is a potent initiator of DNA strand breakage which is an obligatory stimulus for activation of nuclear enzyme, poly-ADP ribosyl synthase or polymerase (PARP) excess activation of PARP can kill cell by depleting NAD+ and energy production, and this may be one of the mechanism by which cells with excess DNA damage are eliminated ( which undergoes necrosis or apoptosis). 68 pp. Englisch.

Seller Inventory # 9783330014213

Title
Characterization of Peroxynitrite modified Glycated DNA
Author
Rizwan Ahmad
Publisher
LAP Lambert Academic Publishing Dez 2016
Publication year
2016
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3330014210
ISBN 13
9783330014213
Item weight
119 grams
Dimensions
220x150x5 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany