Characterisation of SCCmec Elements in Staphylococci

Language: English

Published by LAP LAMBERT Academic Publishing Feb 2014, 2014

3659492469 / 9783659492464

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This item is printed on demand - Print on Demand Titel. Neuware -In staphylococci, resistance to ß-lactam antibiotics is based on the presence of PBP2a encoded by the mecA gene, which is associated to a mobile genetic element, called the staphylococcal cassette chromosome mec (SCCmec). SCCmec is a genomic island of variable size (range 21-67 Kb), integrated at the 3' end of the orfX gene, located near the chromosomal origin of replication. The SCCmec is composed of two central elements, the mec complex containing mecA and intact or truncated forms of its regulatory genes (mecI and mecR1) and the ccr complex that contains recombinases responsible for the integration and excision of this element from the chromosome. Up until to now, eleven major types of SCCmec (I-XI) have been identified in S. aureus. In addition, several SCCmec subtypes and SCC non-mec types have been reported. In this study, we provide insights into the molecular epidemiology of coagulase-negative staphylococci other than S. epidermids through the description of the diversity of clonal types and SCC elements. We also provide a detailed analysis on the most likely contribution of S. hominis and S. haemolyticus species to SCCmec evolution.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 228 pp. Englisch.…

Seller Inventory # 9783659492464

Title
Characterisation of SCCmec Elements in Staphylococci
Author
Ons Bouchami
Publisher
LAP LAMBERT Academic Publishing Feb 2014
Publication year
2014
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659492469
ISBN 13
9783659492464
Item weight
358 grams
Dimensions
220x150x15 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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