Cerebral Signal Transduction: From First to Fourth Messengers (Contemporary Neuroscience) : From First to Fourth Messengers
Language: English
Published by Humana, 2000
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 171.11
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Add to basketItem description from seller
Neu Neu - Neuware, Importqualität, auf Lager - Since the pioneering discovery of cyclic AMP four decades ago, a multitude of signaling pathways have been uncovered in which an extracellular signal (first messenger) impacts the cell surface, thereby triggering a cascade that ultimately acts on the cell nucleus. In each cascade the first messenger gives rise to the appearance of a second messenger such as cyclic AMP, cyclic GMP, or diacylglycerol, which in turn triggers a third messenger, a fourth messenger, and so forth. Many advances in elucidating such pathways have been made, including efforts to link messenger molecules to brain processes operative in health or disease. However, the latter type of information, relating signaling pathways to brain function, is scattered across a variety of publication media, which makes it difficult to integrate the multiple roles of different signaling cascades into our understanding of brain function in health and disease. The primary aim of Cerebral Signal Transduction: From First to Fourth Messengers, therefore, is to offer a comprehensive picture of the recent advances made in the signaling field as it relates to neuronal and cere bral function. The current state of progress provides an exciting opportunity for such a comprehensive focus because molecular tools have become available to selectively remove, reduce, or enhance spe cific components in the signaling pathways, e. g. , by interfering with the genes encoding key proteins. In addition, the increased awareness of crosstalk between different signaling cascades has revealed many possibilities for changes in gene expression underlying long-term changes in brain function.…
Seller Inventory # INF1000764782
- Title
- Cerebral Signal Transduction: From First to Fourth Messengers (Contemporary Neuroscience) : From First to Fourth Messengers
- Author
- Maarten E. A. Reith
- Publisher
- Humana
- Publication year
- 2000
- Condition
- Neu
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0896036081
- ISBN 13
- 9780896036086
- Item weight
- 803 grams
- Dimensions
- 237x159x29
"Synopsis" may belong to another edition of this title.
From the Back Cover
Cutting-edge and comprehensive, Cerebral Signal Transduction: From First to Fourth Messengers advances our understanding of the mechanistic underpinnings of complex behavioral processes and clinically relevant brain diseases. A major contribution to the development of the novel pharmacotherapeutics targeting downstream events in the cascade of second, third, and fourth messengers, it will serve experimental and clinical neuroscientists as today's best and most complete guide to neuronal signaling.
"About the title" may belong to another edition of this title.
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