Cellular Responses to AIDS-Virus Infection : Understanding the Antiviral Efficacy and Breadth of CD8+ T Lymphocytes against Simian Immunodeficiency Virus
Language: English
Published by VDM Verlag Dr. Müller, VDM Verlag Dr. Müller E.K., 2008
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 75.14
Quantity: 2 available
Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - In 2007, approximately 33 million people were living with HIV/AIDS worldwide, while an estimated 2.5 million new infections occurred and 2.1 million AIDS-related deaths. With >95% of new infections occurring in low and middle income countries with limited access to antiretroviral therapy, the development of a prophylactic HIV vaccine remains one of the world's top public health priorities. Many studies illustrate the important role of CD8+ T lymphocytes, also known as cytotoxic T lymphocytes (CTL), in controlling HIV and simian immunodeficiency virus (SIV) replication. However, the correlates of immune protection remain unknown. The SIV-infected rhesus macaque is the most widely used animal model for studying HIV infection. We enhanced the utility of this model by evaluating the breadth of novel, SIV-specific CTL responses in infected macaques. We then examined the antiviral efficacy of these SIV-specific CTL using a novel viral suppression assay. This information may be important in determining the type of CTL epitopes to be targeted in future HIV vaccines. This research should be especially useful for those studying cellular immune responses against AIDS-virus infection.…
Seller Inventory # 9783836492867
- Title
- Cellular Responses to AIDS-Virus Infection : Understanding the Antiviral Efficacy and Breadth of CD8+ T Lymphocytes against Simian Immunodeficiency Virus
- Author
- John Loffredo
- Publisher
- VDM Verlag Dr. Müller, VDM Verlag Dr. Müller E.K.
- Publication year
- 2008
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3836492865
- ISBN 13
- 9783836492867
- Item weight
- 409 grams
- Dimensions
- 220x150x16 mm
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