Cellular Peptide Hormone Synthesis and Secretory Pathways

Language: English

Published by Springer Berlin Heidelberg, Springer Berlin Heidelberg Mär 2010, 2010

3642118348 / 9783642118340

Series: Book 26 of 66 - Results and Problems in Cell Differentiation

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This item is printed on demand - Print on Demand Titel. Neuware -The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone. Receptor binding subsequently elicits action of the target cells. This concept has been seriously challenged by modern biochemistry and cell biology. Thus, it is now well established that the gene of a specific peptide hormone may be expressed in different types of endocrine cells, in neurons, and in some instances also in adipocytes, myocytes, osteoblasts, and immune cells. Today, only a few hormones ¿ including the old master hormone insulin ¿ represent the original endocrine paradigm. Instead, the widespread cellular synthesis now raises the qu- tion of how the body maintains the regulation of its functions by peptide hormones when a hormone may originate from a variety of cells.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch. …

Seller Inventory # 9783642118340

Title
Cellular Peptide Hormone Synthesis and Secretory Pathways
Author
Jens R. Bundgaard
Publisher
Springer Berlin Heidelberg, Springer Berlin Heidelberg Mär 2010
Publication year
2010
Condition
Neu
Binding
Buch
Language
English
ISBN 10
3642118348
ISBN 13
9783642118340
Item weight
587 grams
Dimensions
241x160x20 mm
Series
Book 26 of 66: Results and Problems in Cell Differentiation

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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