Cell Separation : Fundamentals, Analytical and Preparative Methods

Language: English

Published by Springer Berlin Heidelberg, 2010

3642094546 / 9783642094545

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Druck auf Anfrage Neuware - Printed after ordering - Cell separation, which was once limited to merely being a basic technique for fractionating different cell populations, has come a long way in the last two decades. New, advanced and more speci c and selective techniques have emerged as the demand for isolating a speci c cell type for various biological applications has increased. Ef cient and cost-effective techniques for fr- tionation and isolation of target cell types are necessary to provide pure cell populations for diagnostics, biotechnological and biomedical applications. One can see a considerable need, both in biomedical research and in di- nostic medicine, for the speci c separation of a discrete population of cells from a mixture. For example, in the eld of tissue engineering, isolation of stemcellsfromtissuesororgansisofparticularlygreatimportance.Moreover, understanding cell developmental pathways becomes increasingly signi cant as diagnosis and treatment of diseases turns more to the molecular level. The diagnosis of cell-related diseases requires methods of detection, isolation and theanalysisofindividualcells,regardlessoftheirrelativecontentinthetissue. Since cell-based therapies now turn towards more realistic medical options, developing an effective separation system for large-scale cell separation has becomechallengingresearchgoalforcellbiologistsandbiotechnologists.The ideal technique should provide in a short time a good yield of cells with high puritywhile maintaining cellfunction.Despite the growingneed formethods to separate cells into cell subpopulations, the existing cell-separation te- niques stillhave somelimitations when the desired degree ofperformance on apreparativescaleisrequired.Wewillseemoreresearchfocusinthisdirection in the future. The traditional techniques of micro ltration, ultra ltration and ultrac- trifugation, which exploit differences in cell size, shape and density, have remainedtheworkhorsesdespitelowspeci cityandproblemswithscalingup.…

Seller Inventory # 9783642094545

Title
Cell Separation : Fundamentals, Analytical and Preparative Methods
Author
Igor Yu Galaev
Publisher
Springer Berlin Heidelberg
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3642094546
ISBN 13
9783642094545
Item weight
341 grams
Dimensions
235x155x13 mm

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