Cell-Extracellular Matrix Interactions in Cancer
Language: English
Published by Springer, 2009
- Hardcover
- Used
Seller: Mispah books, Redhill, Surrey, United KingdomMispah books
AbeBooks seller since April 15, 2021
Condition: Used - As new
£ 178.00
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- Title
- Cell-Extracellular Matrix Interactions in Cancer
- Publisher
- Springer
- Publication year
- 2009
- Condition
- Like New
- Book Type
- book
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 1441908137
- ISBN 13
- 9781441908131
Cancer was thought to originate from alterations in intercellular signaling that resulted in the transformation of cells, their uncontrolled proliferation and metastasis. There is now an increasing body of evidence demonstrating that the surrounding matrix and cell-matrix interactions are also major players in this process. Cells adhere and receive signals from various extracellular matrices via transmembrane receptors, the best known of which are the heterodimeric glycoproteins, integrins.
"Synopsis" may belong to another edition of this title.
From the Back Cover
Cells require interactions with extracellular matrix (ECM) components in order to undergo normal morphogenesis with respect to organogenesis. ECM plays a significant role in regulating numerous cellular functions, like cell shape, adhesion, migration, proliferation, polarity, differentiation and apoptosis. In pathological conditions such as cancer, increased synthesis of certain ECM components and/or increased breakdown with consequent generation of ECM cleavage products can contribute to cancer growth and progression. That many growth factors (i.e. FGF, VEGF) are stored in the ECM milieu and are released upon protease-dependent cleavage further confirms the importance of ECM in regulating cell functions.
Cell-Extracellular Matrix Interactions in Cancer describes how ECM creates a niche for tumor formation and the contribution of ECM components and their respective receptors in the development and spread of cancer.
"About the title" may belong to another edition of this title.
Mispah books
Redhill, Surrey, United Kingdom
AbeBooks seller since April 15, 2021
Shipping rates from United Kingdom to U.S.A.
| Item | 14 to 15 business days | 9 to 10 business days |
|---|---|---|
| First item | £ 25.00 | £ 27.00 |
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We have collection of General books ,Science Books, Fiction & Academic Books. we ship from multiple location. Delhi, US and UK Return Address Mispah books flat4 , Centenary court, 30 Warwick Road Redhill , SURRE RH1 1FQ United Kingdom
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