Catalysis in Asymmetric Synthesis
Language: English
Published by Wiley Mär 2009, 2009
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
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Neuware - Catalysis in Asymmetric Synthesis, 2nd Edition Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists. Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods. Topics covered include: - Reduction of alkenes, ketones and imines - Nucleophilic addition to carbonyl compounds - Catalytic carbon-carbon bond forming reactions - Catalytic reactions involving metal carbenoids - Conjugate addition reactions Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist. …
Seller Inventory # 9781405190916
- Title
- Catalysis in Asymmetric Synthesis
- Author
- Jonathan M J Williams
- Publisher
- Wiley Mär 2009
- Publication year
- 2009
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 1405190914
- ISBN 13
- 9781405190916
- Edition
- 2nd Edition
- Item weight
- 703 grams
- Dimensions
- 229x152x25 mm
Catalysis in Asymmetric Synthesis, 2nd Edition
Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists.
Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.
Topics covered include:
- Reduction of alkenes, ketones and imines
- Nucleophilic addition to carbonyl compounds
- Catalytic carbon-carbon bond forming reactions
- Catalytic reactions involving metal carbenoids
- Conjugate addition reactions
Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.
"Synopsis" may belong to another edition of this title.
About the Author
Dr Vittorio Caprio, Lecturer in Organic and Medicinal Chemistry in the Department of Chemistry, University of Auckland, New Zealand. His research interests lie in the application of synthetic organic methods to the synthesis of bioactive natural products of diverse structure. A central aim is the efficient and elegant syntheses of target core structures in a stereocontrolled manner using nature as the source of chirality. The ultimate goal is to use natural medicines as the basis for designing and synthesizing drugs of greater therapeutic value.
Professor Jonathan MJ Williams (author of the first edition), Department of Chemistry, University of Bath, UK. Research involves with the use of transition metals for the synthesis of useful organic molecules. In particular, we have been developing reactions using 'borrowing hydrogen.' In this chemistry, ruthenium or iridium catalysts temporarily remove hydrogen to give an aldehyde. This aldehyde then reacts to give an alkene (or imine) and the hydrogen is then returned to give a C-C or C-N bond. These procedures allow alcohols to be used as alkylating agents in place of more conventional, but often toxic/mutagenic alkyl halides.
"About the title" may belong to another edition of this title.
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