Cannabinoids

Language: English

Published by Springer Berlin Heidelberg, 2005

354022565X / 9783540225652

Series: Book 4 of 124 - Handbook of Experimental Pharmacology

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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Druck auf Anfrage Neuware - Printed after ordering - Less than 20 years ago the eld of cannabis and the cannabinoids was still c- sidered a minor, somewhat quaint, area of research. A few groups were active in the eld, but it was already being viewed as stagnating. The chemistry of cannabis 9 9 was well known, -tetrahydrocannabinol ( -THC), identi ed in 1964, being the only major psychoactive constituent and cannabidiol, which is not psychoactive, possibly contributing to some of the effects. These cannabinoids and several s- thetic analogs had been thoroughly investigated for their pharmacological effects. Their mode of action was considered to be non-speci c. The reasons for this - sumption were both technical and conceptual. On the technical side, it had been shown that THC was active in both enantiomeric forms (though with a different level of potency) and this observation was incompatible with action on biological substrates-a receptor, an enzyme, an ion channel-which react with a single stereoisomer only. The conceptual problem related to THC activity. This had been pointed out by several highly regarded research groups that had shown that many of the effects seen with cannabinoids were related to those of biologically active lipophiles, and that many of the effects of THC, particularly chronic ones, were comparable to those seen with anaesthetics and solvents.…

Seller Inventory # 9783540225652

Title
Cannabinoids
Author
Roger G. Pertwee
Publisher
Springer Berlin Heidelberg
Publication year
2005
Condition
Neu
Binding
Buch
Language
English
ISBN 10
354022565X
ISBN 13
9783540225652
Item weight
1,275 grams
Dimensions
241x160x48 mm
Series
Book 4 of 124: Handbook of Experimental Pharmacology

AHA-BUCH GmbH

Einbeck, Germany

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