Cancer through the Lens of Evolution and Ecology
Sold by Biblios, Frankfurt am main, HESSE, Germany
AbeBooks Seller since 10 September 2024
New - Hardcover
Condition: New
Ships from Germany to U.S.A.
Quantity: 3 available
Add to basketSold by Biblios, Frankfurt am main, HESSE, Germany
AbeBooks Seller since 10 September 2024
Condition: New
Quantity: 3 available
Add to basketCancer cells exist in an ever-changing “ecology” and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms.
Key Features
Jason A. Somarelli is a molecular biologist, who received his doctoral degree from Florida International University in Miami, FL and was an American Cancer Society postdoctoral fellow at Duke University. He is currently an Assistant Professor in the Department of Medicine at Duke University. Somarelli serves as the Director of Research for the Duke Cancer Institute Comparative Oncology Group and is the Director of the Duke University Marine Laboratory Scholars in Marine Medicine Program. Dr. Somarelli’s research uses evolutionary and ecology paradigms to understand molecular adaptations to extreme environments. His work spans diverse topics, such as the evolutionary pressures faced by cancer cells during drug treatment and metastatic spread, the molecular adaptations of whales and other marine mammals to low oxygen conditions, and the evolution of microbes to use plastic as a nutrient source. In addition to his scholarly activities, Dr. Somarelli is passionately involved in training and education, leading multiple outreach and research training programs for high school students and undergraduates in an effort to enhance diversity in STEM careers.
Norman A. Johnson is an evolutionary geneticist, who received his doctoral degree from the University of Rochester and was a postdoctoral fellow at the University of Chicago. He is now an adjunct professor in the Biology department at the University of Massachusetts at Amherst. Johnson has also taught at the University of Chicago, the University of Texas at Arlington, and Hampshire College. Most of his research has been on the genetics and evolution of why hybrids between species are often sterile or inviable. Other research interests include the evolution of sex chromosomes, the evolution of extremely large dietary niches in insects, conflict between different parts of the genome, and the interplay between the relaxation of selection and the loss of traits. Johnson’s first book, Darwinian Detectives: Revealing the Natural History of Genes and Genomes (Oxford University Press, 2007), examines how biologists infer the action of natural selection and other evolutionary processes from DNA sequence information. More recently, he wrote Darwin’s Reach: 21st Century Applications of Evolutionary Biology (CRC Press, 2022). This book explores how ideas and information from evolutionary are being used in diverse ways in the realms of health, food, the environment, and society at large. Dr. Johnson has been active in science communication and outreach; notably, he co-led the National Evolutionary Synthesis Center working group on communicating the relevance of human evolution.
"About this title" may belong to another edition of this title.
If you are a consumer you can withdraw from the contract in accordance with the following. Consumer means any natural person who is acting for purposes which are outside his trade, business, craft or profession.
Information regarding the right of withdrawal
Statutory right to withdraw
You have the right to withdraw from this contract within 14 days without giving any reason.
The withdrawal period will expire after 14 days from the day on which you acquire, or a third party other than the carrier and indicated by you acquires, physical possession of the last good or the last lot or piece.
To exercise the right of withdrawal, electronically fill in and submit a clear statement on our website, under "My Purchases" in "My Account". We will communicate to you an acknowledgement of receipt of such a withdrawal on a durable medium (e.g. by e-mail) without delay.
To meet the withdrawal deadline, it is sufficient for you to send your communication concerning your exercise of the right of withdrawal before the withdrawal period has expired.
Effects of withdrawal
If you withdraw from this contract, we will reimburse to you all payments received from you, including the costs of delivery (except for the supplementary costs arising if you chose a type of delivery other than the least expensive type of standard delivery offered by us).
We may make a deduction from the reimbursement for loss in value of any goods supplied, if the loss is the result of unnecessary handling by you.
We will make the reimbursement without undue delay, and not later than 14 days after the day on which we are informed about your decision to withdraw from this contract.
We will make the reimbursement using the same means of payment as you used for the initial transaction, unless you have expressly agreed otherwise; in any event, you will not incur any fees as a result of such reimbursement.
We may withhold reimbursement until we have received the goods back, or you have supplied evidence of having sent back the goods, whichever is the earliest.
You shall send back the goods or hand them over to Biblios, frankfurt am main, Germany, without undue delay and in any event not later than 14 days from the day on which you communicate your withdrawal from this contract to us. The deadline is met if you send back the goods before the period of 14 days has expired. You will have to bear the direct cost of returning the goods. You are only liable for any diminished value of the goods resulting from the handling other than what is necessary to establish the nature, characteristics and functioning of the goods.
Exceptions to the right of withdrawal
The right of withdrawal does not apply to:
| Order quantity | 25 to 45 business days | 8 to 14 business days |
|---|---|---|
| First item | £ 8.58 | £ 16.13 |
Delivery times are set by sellers and vary by carrier and location. Orders passing through Customs may face delays and buyers are responsible for any associated duties or fees. Sellers may contact you regarding additional charges to cover any increased costs to ship your items.