Calcium Entry Blockers in Cardiovascular and Cerebral Dysfunctions
Language: English
Published by Springer, Springer, 2011
Series: Book 27 of 253 - Developments in Cardiovascular Medicine
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 50.51
Quantity: 1 available
Add to basketItem description from seller
Druck auf Anfrage Neuware - Printed after ordering - 2 The free internal Ca+ concentration in human red cells is set according to the leak 2 and-pump principle: There is a finite passive Ca+ influx at the physiological 2 2 Ca+ -gradient across the membrane which is compensated by Ca+ pumping in the outward direction with a rate given by the degree of saturation of the A TP-fuelled Ca 2 pump at the steady-state internal Ca+ concentration. Simons (1982) recently devised a method allowing the measurement of the steady 2 2 state internal Ca+ concentration. Cells are suspended in media of different Ca+ con 2 2 tent whose Ca+ concentration is monitored by a Ca+ -selective electrode. When the cells are lysed (by digitonin) there is an upward or downward deflection of the elec 2 trode signal. At the point of zero deflection, the cellular Ca+ concentration equals that 2 of the medium. The result is, that in fresh human red blood cells the Ca+ concentra tion is ;;;; O.4,uM (this is an upper estimate; the true value may be considerably lower).…
Seller Inventory # 9789400960350
- Title
- Calcium Entry Blockers in Cardiovascular and Cerebral Dysfunctions
- Author
- T. Godfraind
- Publisher
- Springer, Springer
- Publication year
- 2011
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 9400960352
- ISBN 13
- 9789400960350
- Item weight
- 534 grams
- Dimensions
- 244x156x19 mm
- Series
- Book 27 of 253: Developments in Cardiovascular Medicine
"Synopsis" may belong to another edition of this title.
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