Botulinum Neurotoxins
Language: English
Published by Springer Berlin Heidelberg, 2015
Series: Book 197 of 322 - Current Topics in Microbiology and Immunology
- Softcover
- New
Condition: New
£ 127.09
Quantity: Over 20 available
Add to basketItem description from seller
Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by leading experts in the field botulinum neurotoxinsProvides the current status of basic botulinum neurotoxin researchProvides in depth articles on neurotoxins for further medical applications by means of recombinant technologies.
Seller Inventory # 449057723
- Title
- Botulinum Neurotoxins
- Author
- Rummel, Andreas|Binz, Thomas
- Publisher
- Springer Berlin Heidelberg
- Publication year
- 2015
- Condition
- New
- Binding
- Soft cover
- Language
- English
- ISBN 10
- 3642448895
- ISBN 13
- 9783642448898
- Series
- Book 197 of 322: Current Topics in Microbiology and Immunology
- Seller catalogs
- Mathematik/Naturwissenschaften/Technik/Medizin
"Synopsis" may belong to another edition of this title.
From the Back Cover
Botulinum neurotoxins are the most toxic natural substances and represent a major threat to the population when intentionally released in bioterrorist attacks. On the other hand, during the past two decades botulinum neurotoxins have become established as indispensable drugs for the treatment of a variety of severe neurological disorders. The need for efficient countermeasures as well as the expansion into additional fields of therapeutic application, call for comprehensive information on the botulinum neurotoxin molecules and their mode of action. Our knowledge of this subject has made great strides in recent years, setting the stage for the development of new botulinum neurotoxin-based molecules and novel applications.
This book reviews the current status of basic botulinum neurotoxin research. The first part describes the genetic variability of the toxin-producing bacteria, and sheds light on each step from toxin ingestion to the abrogation of synaptic signaling including the intestinal passage and absorption, nerve cell binding and entry, and intracellular substrate cleavage. The remaining chapters detail progress made in detection methods for botulinum neurotoxins, the development of botulinum neurotoxin inhibitors, and strategies to refine the neurotoxins for further medicinal applications by means of recombinant technologies.
"About the title" may belong to another edition of this title.
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