Biosynthesis

Language: English

Published by Springer, Springer Feb 2000, 2000

3540669698 / 9783540669692

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This item is printed on demand - Print on Demand Titel. Neuware -The present volume is the first of two planned to provide state-of-the-art expert reviews of central topics in modern natural products chemistry and secondary metabolism. Many scientists not directly involved in these areas still view the field of natural products as focused primarily on the isolation,structure elucidation, and cataloging of new compounds (i. e. ¿grind and find¿),or on their chemical synthesis. However,two revolutions in experimental techniques since the early 1950¿s have completely transformed the understanding of chemical and biological relationships between highly diverse natural products. The first was the use isotopes to label precursors and follow the fate of key atoms during biochemical transformations to a final product. Advances in methodology that began in the mid-1970¿s,especially using NMR to detect stable isotopes,dramatically expanded the level of mechanistic detail available to study in vivo conversions of secondary metabolites. The second revolution started in the late 1980¿s as researchers developed methods to identify,purify and genetically manipulate individual enzymes - sponsible for the intricate steps leading to complex natural products. This has expanded the field from building an encyclopaedia of natural materials to being able to initiate control of biochemical pathways to secondary metabolites. Recent advances suggest it may soon be possible to rationally manipulate biochemical pathways in vivo to rapidly produce almost any target molecule,including n- natural variants,in substantial quantity.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 204 pp. Englisch.

Seller Inventory # 9783540669692

Title
Biosynthesis
Author
F. J. Leeper
Publisher
Springer, Springer Feb 2000
Publication year
2000
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3540669698
ISBN 13
9783540669692
Edition
2nd Edition
Item weight
355 grams
Dimensions
235x155x13 mm

buchversandmimpf2000

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