Biomolecular and Safety Considerations of Phytopharmaceuticals

This book provides a comprehensive and holistic overview of the evolving field of phytopharmaceuticals, bridging ancient practices with modern technological advancements. It begins by exploring current trends and the evolution of phytomedicine across continents, with a focus on screening, extraction, purification, identification, standardization, and quality control of phytopharmaceuticals. It highlights cutting-edge techniques, like high-throughput screening, omics integration, and the application of artificial intelligence in phytomedicine research. The book presents the biomechanics of phytocompounds as antipathogenic agents, their therapeutic applications, and innovative strategies for delivering phytochemical compounds, including nanostructured systems. Furthermore, the book assesses the impact of herb-drug interactions on bioactivity and safety, biopharmaceutical challenges, and safety and toxicology considerations crucial for the use of phytomedicines. It reviews phytopharmaceutical regulations and public perceptions and includes case studies of marketed phytomedicines. The book presents case studies on marketed phytomedicines, providing real-world insights into the successful application and commercialization of phytopharmaceuticals. This book is an essential resource for researchers, clinicians, and professionals in the fields of herbal medicine, pharmacology, and ethnopharmacology.

Key Features

• Explores the evolution of phytomedicine from ancient practices to modern advancements, offering a comprehensive historical perspective
• Highlights cutting-edge methods such as high-throughput screening, omics integration, and the use of artificial intelligence in phytomedicine research
• Presents innovative delivery strategies, including nanostructured systems, to enhance the bioavailability and effectiveness of phytochemical compounds
• Addresses biopharmaceutical challenges and safety considerations, discussing the complexities of formulation, stability, and regulatory compliance in phytomedicine
• Includes case studies and regulatory insights to provide real-world examples of successful phytopharmaceutical applications and commercialization

Rakesh Kumar Tekade is a distinguished pharmaceutical scientist and Professor in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad. His career spans over a decade of academic and research excellence across India, the USA, the UK, and Malaysia. Dr. Tekade is a recipient of numerous prestigious awards, including the Commonwealth Fellowship (UK), National Doctoral Fellowship (AICTE-NDF), Irish Government Postdoctoral Award (IRISH-PDF), CSIR-SRF, AICTE-JRF, and the Troikaa Pharm Innova Award. His research focuses on the development of translational and targeted nano-biomaterials for biomedical applications. He has co-authored over 400 publications (with more than 18000+ citations and an H-index of 67), edited 12 reference books, and holds 12 patents, as well as one technology transfer to his credit. Dr. Tekade has been recognized as a top 2% researcher in pharmacy and pharmacology by Stanford University and Elsevier. Dr. Tekade has supervised numerous postdoctoral researchers, Ph.D. students, and master’s students and is the principal investigator for DST, DBT, and ICMR-funded projects. He has also served on various nationally and internationally recognized committees and as a reviewer for multiple international journals and grant agencies.

Shailendra Saraf is a notable expert and a renowned academician in the Arena of Pharmaceutical Disciplines. As the Director of the National Institute of Pharmaceutical Education and Research, Ahmedabad, he leverages his extensive experience in academic leadership. Dr. Saraf has played a pivotal role in various national, statutory, regulatory, and accreditation bodies and maintains active connections with several national and international professional organizations. He has successfully completed multiple research projects funded by national extramural funding agencies and supervised over a dozen Ph.D. candidates. He has authored over 200 research/review papers, filed 10 patents, garnered more than 10,000 citations, and has an H-index of 46. He is on editorial boards and a reviewer for numerous national and international journals. He has delivered keynote speeches and chaired sessions in various seminars, conferences, and workshops globally.