Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance (Hardcover)
Language: English
Published by Elsevier Science Publishing Co Inc, San Diego, 2020
- Hardcover
- New
Seller: Grand Eagle Retail, Bensenville, IL, U.S.A.Grand Eagle Retail
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£ 158.55
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Seller Inventory # 9780128213100
- Title
- Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance (Hardcover)
- Author
- Andrew Freywald
- Publisher
- Elsevier Science Publishing Co Inc, San Diego
- Publication year
- 2020
- Condition
- new
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0128213108
- ISBN 13
- 9780128213100
Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance.
Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges.
- Provides the most updated knowledge on the mechanisms of cancer drug resistance and the emerging therapeutic approaches reviewed by experts in the field
- Brings detailed analyses of most important recently reported developments related to drug resistance and their relevance to overcoming it in cancer patients
- Discusses in-depth molecular mechanisms and novel concepts of cancer resistance to conventional and advanced therapies
"Synopsis" may belong to another edition of this title.
About the Author
Dr. Franco J. Vizeacoumar, obtained his PhD in cell biology at the University of Alberta, Canada, and did his post-doctorate at the University of Toronto, Canada. His lab is working on developing genotype-directed cancer therapies for solid tumors by applying basic biological concepts called synthetic lethality and synthetic dosage lethality. The long term goal of his research group is to build a unified human genetic network that will capture genetic dependencies of cancer cells and define key therapeutic targets. The work in the Vizeacoumar lab has been supported by multiple granting agencies, such as CIHR, SCA, CRS, SHRF, CFI, TFRI, PCC, and also by the Be Like Bruce organization and the College of Medicine at the University of Saskatchewan.
"About the title" may belong to another edition of this title.
Grand Eagle Retail
Bensenville, IL, U.S.A.
AbeBooks seller since October 12, 2005
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