Biological Functions of Proteinases : 30. Colloquium, 26.-28. April 1979

Language: English

Published by Springer Berlin Heidelberg, 2011

3642813976 / 9783642813979

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Druck auf Anfrage Neuware - Printed after ordering - Proteinases were among the first enzymes to be investigated biochemi cally, and purification and crystallization especially of proteolytic enzymes of the digestive tract has contributed much to our present knowledge of enzymic structure and mechanisms of catalysis. However, for a long time little has been known about the functional aspects of proteinases. The only exception from this have been the digestive tract enzymes responsible for extracellular catalysis of protein breakdown and supply of amino acids for new-protein assembly and nitrogen metab olism in the respective organs. The work of Schoenheimer, summarized for the first time in 1942 in a paper entitled 'Dynamic state of body constituents', showed that continuous turnover of proteins takes place in cells. But scientists did not pay much attention to these findings at that time. The continuous accumulation of knowledge of a variety of intracellular proteolytic processes during the past decades has greatly stimulated research in this field. The central role of proteo lysis in cellular regulation has become fully evident during recent years. It is the aim of the 30th Mosbach Colloquium to present an over view of our present knowledge of proteinase structure, function and control. The relationship between globular protein structure of a proteinase and induction of enzymic activity will be discussed for trypsin and trypsinogen activation. One significant proteinase action is the total degradation of proteins to serve cellular needs under different condi tions.

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Title
Biological Functions of Proteinases : 30. Colloquium, 26.-28. April 1979
Author
H. Tschesche
Publisher
Springer Berlin Heidelberg
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3642813976
ISBN 13
9783642813979
Item weight
522 grams
Dimensions
244x170x17 mm

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