Bioinformatics Algorithms: Techniques and Applications: 03 (Wiley Series in Bioinformatics)
Language: English
Published by John Wiley & Sons, 2008
- Hardcover
- New
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- Title
- Bioinformatics Algorithms: Techniques and Applications: 03 (Wiley Series in Bioinformatics)
- Author
- Zelikovsky Alexander Mandoiu Ion
- Publisher
- John Wiley & Sons
- Publication year
- 2008
- Condition
- New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 0470097736
- ISBN 13
- 9780470097731
This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers:
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General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, seeding, and approximation algorithms
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Algorithms and tools for genome and sequence analysis, including formal and approximate models for gene clusters, advanced algorithms for non-overlapping local alignments and genome tilings, multiplex PCR primer set selection, and sequence/network motif finding
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Microarray design and analysis, including algorithms for microarray physical design, missing value imputation, and meta-analysis of gene expression data
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Algorithmic issues arising in the analysis of genetic variation across human population, including computational inference of haplotypes from genotype data and disease association search in case/control epidemiologic studies
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Algorithmic approaches in structural and systems biology, including topological and structural classification in biochemistry, and prediction of protein-protein and domain-domain interactions
Each chapter begins with a self-contained introduction to a computational problem; continues with a brief review of the existing literature on the subject and an in-depth description of recent algorithmic and methodological developments; and concludes with a brief experimental study and a discussion of open research challenges. This clear and approachable presentation makes the book appropriate for researchers, practitioners, and graduate students alike.
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About the Author
Alexander Zelikovsky, PhD, is Associate Professor in the Computer Science Department at Georgia State University. His research focuses on discrete algorithms and their applications in bio-technology, bioinformatics, VLSI computer-aided design, and wireless networks.
"About the title" may belong to another edition of this title.
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