Bioelectricity: A Quantitative Approach

Plonsey, Robert,Barr, Roger C.

ISBN 10: 0306428946 / ISBN 13: 9780306428944

Published by Plenum Press, 1991

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Synopsis:

This text is an introduction to electrophysiology, following a quantitative approach. The first chapter summarizes much of the mathematics required in the following chapters. The second chapter presents a very concise overview of the general principles of electrical fields and current flow, mostly es­ tablished in physical science and engineering, but also applicable to biolog­ ical environments. The following five chapters are the core material of this text. They include descriptions of how voltages come to exist across membranes and how these are described using the Nernst and Goldman equations (Chapter 3), an examination of the time course of changes in membrane voltages that produce action potentials (Chapter 4), propagation of action potentials down fibers (Chapter 5), the response of fibers to artificial stimuli such as those used in pacemakers (Chapter 6), and the voltages and currents produced by these active processes in the surrounding extracellular space (Chapter 7). The subsequent chapters present more detailed material about the application of these principles to the study of cardiac and neural electrophysiology, and include a chapter on recent developments in mem­ brane biophysics. The study of electrophysiology has progressed rapidly because of the precise, delicate, and ingenious experimental studies of many investigators. The field has also made great strides by unifying the numerous experimental observations through the development of increasingly accurate theoretical concepts and mathematical descriptions. The application of these funda­ mental principles has in turn formed a basis for the solution of many different electrophysiological problems.

Review:

Praise for Previous Editions:

"This fine text, by two well-known bioengineering professors at Duke University, is an introduction to electrophysiology aimed at engineering students. Most of its chapters cover basic topics in electrophysiology: the electrical properties of the cell membrane, action potentials, cable theory, the neuromuscular junction, extracellular fields, and cardiac electrophysiology. The authors discuss many topics that are central to biophysics and bioengineering [and] the quantitative methods [they] teach will surely be productive in the future."

IEEE Engineering in Medicine and Biology

"The authors’ goal in producing this book was to provide an introductory text to electrophysiology, based on a quantitative approach. In attempting to achieve this goal, therefore, the authors have opened the book with a useful, and digestible, introduction to various aspects of the mathematics relevant to this field, including vectors, introduction to Laplace, Gauss’s theorem, and Green’s theorem. This book will be useful for students in medical physics and biomedical engineering wishing to enter the field of electrophysiological investigation. It will also be helpful for biologists and physiologists who wish to understand the mathematical treatment of the processes and signals at the center of the interesting interdisciplinary field."

Medical and Biomedical Engineering and Computing

Bibliographic Details

Title: Bioelectricity: A Quantitative Approach
Publisher: Plenum Press
Publication Date: 1991
Binding: Hardcover
Condition: Good