Bacterial Signal Transduction: Networks and Drug Targets

Language: English

Published by Springer New York Nov 2010, 2010

1441927034 / 9781441927033

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -A decade has passed since Drs. Hoch and Silhavy edited their comprehensive work entitled Two-Component Signal Transduction. This fascinating book encour aged many microbiologists and students to enter the new worldofsignal transduction in microbiology. In 2003, Dr. Inouye edited Histidine Kinase in Signal Transduc tion, which focused on histidine kinases and presented the wealth ofinformation accumulated on this protein family. Bacteria usually possess a numberofTwo-Component Systems (TCSs), rang ing from a few to over 100. InE. coli, 29 histidine kinases, 32 response regulators, and 1histidine-containing phosphor transmitter (HPt) domain have been found by analyses ofthe K-12 genome. Several examples ofin vitro and in vivo cross-talks and signal transductioncascadesbetweenTCSs inE. coli have beenreported,which suggests the existence ofa TCS network (Chapter 1). Interactions among different TCSs enable one system to respond to multiple signals, which is important for bacteria to minutely adjust themselves to complex environmental changes. Such interactions are found or predicted in various bacteria in this book. Many ofthese interactions might be connected by small proteins such as B1500(Chapter 1)and PmrD (Chapter2). More examplesofsuch proteins should be identified in the near future in order to fill-in the missing parts ofthe bacterial signal transduction network, a new paradigm that is increasingly recognized as the signal transduction pathway in bacterial cells. For drug discovery, this pathway is consideredas important as the signal transductionpathway in animal cells (Chapters 15 and 16). 264 pp. Englisch.…

Seller Inventory # 9781441927033

Title
Bacterial Signal Transduction: Networks and Drug Targets
Author
Ryutaro Utsumi
Publisher
Springer New York Nov 2010
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1441927034
ISBN 13
9781441927033
Item weight
503 grams
Dimensions
254x178x15 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany